Discuss This Drug

Pergolide

CHEBI:CHEBI_63617

Definition

A diamine that is ergoline in which the beta-hydrogen at position 8 is replaced by a (methylthio)methyl group and the hydrogen attached to the piperidine nitrogen (position 6) is replaced by a propyl group. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it is used as the mesylate salt in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction.

Chemical Information

Molecular Formula
C19H26N2S
Molecular Mass
314.48800
Charge
0
SMILES
[H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])C[C@@H](CSC)CN2CCC
InChI
InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1
InChIKey
YEHCICAEULNIGD-MZMPZRCHSA-N

Alternative Names

  • (8beta)-8-[(methylsulfanyl)methyl]-6-propylergoline
  • pergolida
  • pergolide
  • pergolidum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:63617
DRON_00010000
8047
oboInOwl#hasDbXref
Wikipedia:Pergolide

Additional References

Wikipedia:Pergolide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:63617
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_111819
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_63706
owl#annotatedSource
t262834
owl#someValuesFrom
t836056
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
8047
oboInOwl#hasDbXref
Wikipedia:Pergolide
oboInOwl#id
CHEBI:63617
oboInOwl#hasAlternativeId
CHEBI:8020
listing_expiration_date
20241231
dosage_form
POWDER
marketing_start_date
20220408
active_ingredient_strength
100 kg/100kg
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
labeler_name
Sichuan Renan Pharmaceutical Co., Ltd
package_marketing_start_date
08-APR-22
generic_name
Pergolide Mesylate
product_ndc
60592-921
spl_id
2393e484-f370-6d02-e063-6394a90aa88e
active_ingredient_name
PERGOLIDE MESYLATE
package_ndc
60592-921-01
package_description
100 g in 1 BOTTLE (60592-921-01)
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_51065
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_63706
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class