Discuss This Drug

Propafenone

CHEBI:CHEBI_63619

Definition

An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.

Chemical Information

Molecular Formula
C21H27NO3
Molecular Mass
341.44400
Charge
0
SMILES
CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1
InChI
InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3
InChIKey
JWHAUXFOSRPERK-UHFFFAOYSA-N

Alternative Names

  • 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone
  • 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
  • 2-(2'-hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone
  • propafenona
  • propafenone
  • propafenonum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
8754
oboInOwl#hasDbXref
Wikipedia:Propafenone
core#notation
CHEBI:63619

Additional References

Wikipedia:Propafenone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
8754
oboInOwl#hasDbXref
Wikipedia:Propafenone
oboInOwl#id
CHEBI:63619
oboInOwl#hasAlternativeId
CHEBI:8465
generic_name
PROPAFENONE HYDROCHLORIDE MICRONIZED
brand_name
Propafenone HCl
brand_name_base
Propafenone HCl
product_ndc
12598-6285
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38070
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BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723856
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_63650
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
labeler_name
Vitruvias Therapeutics
dosage_form
TABLET, COATED
marketing_start_date
19950629
application_number
ANDA078540
route
ORAL
spl_id
a5708c40-e1b3-85a1-e053-2995a90a96e7
package_ndc
12598-6285-5
package_description
25 kg in 1 DRUM (12598-6285-5)
package_marketing_start_date
16-DEC-92
rxcui
861173
manufacturer_name
Vitruvias Therapeutics
active_ingredient_strength
1 h/kg
active_ingredient_name
PROPAFENONE
unii
33XCH0HOCD
spl_set_id
9da7e6d2-64da-43cd-9575-b2b0d5d412dc
upc
0364380184027
brand_name_suffix
SR
core#notation
CHEBI:63619
pharm_class
Antiarrhythmic [EPC]
22-rdf-syntax-ns#type
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t262853
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