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tenofovir (anhydrous)

CHEBI:CHEBI_63625

Definition

A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.

Chemical Information

Molecular Formula
C9H14N5O4P
Molecular Mass
287.21230
Charge
0
SMILES
C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(O)=O
InChI
InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1
InChIKey
SGOIRFVFHAKUTI-ZCFIWIBFSA-N

Alternative Names

  • tenofovir
  • ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid
  • (R)-PMPA
  • anh. tenofovir
  • anhydrous tenofovir
  • tenofovir (anh.)

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Tenofovir
core#notation
CHEBI:63625

Additional References

Wikipedia:Tenofovir

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Tenofovir
oboInOwl#id
CHEBI:63625
core#notation
CHEBI:63625
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_49103
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_134504
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_63717
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_134504
owl#someValuesFrom
t266400
owl#annotatedSource
t262922