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tipranavir

CHEBI:CHEBI_63628

Definition

A pyridine-2-sulfonamide substituted at C-5 by a trifluoromethyl group and at the sulfonamide nitrogen by a dihydropyrone-containing m-tolyl substituent. It is an HIV-1 protease inhibitor.

Chemical Information

Molecular Formula
C31H33F3N2O5S
Molecular Mass
602.66400
Charge
0
SMILES
CCC[C@@]1(CCc2ccccc2)CC(O)=C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1
InChI
InChI=1S/C31H33F3N2O5S/c1-3-16-30(17-15-21-9-6-5-7-10-21)19-26(37)28(29(38)41-30)25(4-2)22-11-8-12-24(18-22)36-42(39,40)27-14-13-23(20-35-27)31(32,33)34/h5-14,18,20,25,36-37H,3-4,15-17,19H2,1-2H3/t25-,30-/m1/s1
InChIKey
SUJUHGSWHZTSEU-FYBSXPHGSA-N

Alternative Names

  • 3'-((1R)-1-((6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-phenethyl-6-propyl-2H-pyran-3-yl)propyl)-5-(trifluoromethyl)-2-pyridinesulfonanilide
  • N-(3-{(1R)-1-[(6R)-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-5,6-dihydro-2H-pyran-3-yl]propyl}phenyl)-5-(trifluoromethyl)pyridine-2-sulfonamide
  • tipranavir

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Reaxys:7698323
DRON_00010000
190548
core#notation
CHEBI:63628

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Reaxys:7698323
DRON_00010000
190548
oboInOwl#id
CHEBI:63628
core#notation
CHEBI:63628
generic_name
Tipranavir
rxcui
603378
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
CAPSULE, LIQUID FILLED
active_ingredient_strength
1 kg/kg
labeler_name
Boehringer Ingelheim Pharma GmbH and Co. KG
manufacturer_name
Boehringer Ingelheim Pharmaceuticals, Inc.
marketing_start_date
20050701
package_marketing_start_date
01-JUL-05
pharm_class_moa
HIV Protease Inhibitors [MoA]
pharm_class
Protease Inhibitor [EPC]
pharm_class_epc
Protease Inhibitor [EPC]
nui
N0000175889
product_ndc
0597-0003
spl_id
5845744e-7dcd-425c-9fde-aed525ca6b31
active_ingredient_name
TIPRANAVIR
package_ndc
0597-0003-02
package_description
120 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0597-0003-02)
brand_name
Aptivus
brand_name_base
Aptivus
application_number
NDA021814
unii
ZZT404XD09
spl_set_id
08982e49-d2eb-4b25-b01a-1be52fd669ef
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35660
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect30690
owl#annotatedSource
t262329
owl#someValuesFrom
t957572