Discuss This Drug

topiramate

CHEBI:CHEBI_63631

Definition

A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine.

Chemical Information

Molecular Formula
C12H21NO8S
Molecular Mass
339.36200
Charge
0
SMILES
CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1
InChI
InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1
InChIKey
KJADKKWYZYXHBB-XBWDGYHZSA-N

Alternative Names

  • 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
  • 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate
  • McN-4853
  • RWJ-17021
  • tipiramate
  • tipiramato
  • Topamax
  • topiramate
  • Topiramate
  • topiramato
  • topiramatum
  • TPM

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
38404
oboInOwl#hasDbXref
Wikipedia:Topiramate
core#notation
CHEBI:63631

Additional References

Wikipedia:Topiramate

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_ndc
65267-103
marketing_start_date
20140614
labeler_name
SHODHANA LABORATORIES PRIVATE LIMITED
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
38404
oboInOwl#hasDbXref
Wikipedia:Topiramate
oboInOwl#id
CHEBI:63631
oboInOwl#hasAlternativeId
CHEBI:9633
brand_name
QUDEXY XR
brand_name_base
QUDEXY
generic_name
topiramate spinkle
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38633
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00698710
package_ndc
70771-1659-9
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
BEAD
application_number
ANDA217869
listing_expiration_date
20241231
spl_id
9972e220-2439-d5f2-e053-2995a90a1860
package_description
50 TABLET in 1 BOTTLE (53002-1547-6)
route
ORAL
upc
0368071308839
active_ingredient_strength
40 kg/40kg
nui
N0000182140
active_ingredient_name
TOPIRAMATE
spl_set_id
57016639-89fe-43ad-89c4-5e7a756dddec
package_marketing_start_date
13-MAR-23
manufacturer_name
Supernus Pharmaceuticals
core#notation
CHEBI:63631
pharm_class_pe
Decreased Central Nervous System Disorganized Electrical Activity [PE]
pharm_class
Cytochrome P450 2C19 Inhibitors [MoA]
pharm_class_moa
Cytochrome P450 2C19 Inhibitors [MoA]
brand_name_suffix
XR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
1494781
unii
0H73WJJ391
has_treatment
http://purl.obolibrary.org/obo/DOID_0070076
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect30749
owl#annotatedSource
t262784
owl#someValuesFrom
t3862133