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Triptorelin

CHEBI:CHEBI_63633

Definition

An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-tryptophyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It is an agonist analogue of gonadotropin-releasing hormone.

Chemical Information

Molecular Formula
C64H82N18O13
Molecular Mass
1311.44870
Charge
0
SMILES
CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O
InChI
InChI=1S/C64H82N18O13/c1-34(2)23-46(56(88)75-45(13-7-21-69-64(66)67)63(95)82-22-8-14-52(82)62(94)72-31-53(65)85)76-58(90)48(25-36-28-70-42-11-5-3-9-40(36)42)78-57(89)47(24-35-15-17-39(84)18-16-35)77-61(93)51(32-83)81-59(91)49(26-37-29-71-43-12-6-4-10-41(37)43)79-60(92)50(27-38-30-68-33-73-38)80-55(87)44-19-20-54(86)74-44/h3-6,9-12,15-18,28-30,33-34,44-52,70-71,83-84H,7-8,13-14,19-27,31-32H2,1-2H3,(H2,65,85)(H,68,73)(H,72,94)(H,74,86)(H,75,88)(H,76,90)(H,77,93)(H,78,89)(H,79,92)(H,80,87)(H,81,91)(H4,66,67,69)/t44-,45-,46-,47-,48+,49-,50-,51-,52-/m0/s1
InChIKey
VXKHXGOKWPXYNA-PGBVPBMZSA-N

Alternative Names

  • (6-D-Tryptophan)luteinizing hormone-releasing hormone
  • (D-Trp6)-GnRH
  • 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycinamide
  • Luteinizing hormone-releasing factor (pig), 6-D-tryptophan
  • pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
  • triptorelin
  • triptorelina
  • triptoreline
  • triptorelinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
38782
oboInOwl#hasDbXref
Wikipedia:Triptorelin
core#notation
CHEBI:63633

Additional References

Wikipedia:Triptorelin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
38782
oboInOwl#hasDbXref
Wikipedia:Triptorelin
oboInOwl#id
CHEBI:63633
generic_name
Triptorelin pamoate
dosage_form
INJECTION, POWDER, FOR SUSPENSION
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
marketing_start_date
20000615
brand_name
TRIPTODUR
brand_name_base
TRIPTODUR
product_ndc
62788-956
application_number
NDA208956
labeler_name
Synergy Health AST, Inc
spl_id
238ef7a9-b849-0651-e063-6394a90a187f
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_63533
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:63633
rxcui
1944389
active_ingredient_strength
11.25 mg/2mL
manufacturer_name
Azurity Pharmaceuticals, Inc.
package_marketing_start_date
07-MAR-02
package_ndc
62788-956-01
package_description
2 mL in 1 VIAL (62788-956-01)
spl_set_id
f41380e7-b830-432d-a5f5-a872932f107e
active_ingredient_name
TRIPTORELIN ACETATE
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_14780
owl#annotatedSource
t262939
owl#someValuesFrom
t638825