Discuss This Drug

valdecoxib

CHEBI:CHEBI_63634

Definition

A member of the class of isoxazoles that is isoxazole which is substituted at positions 3, 4 and 5 by phenyl, p-sulfamoylphenyl and methyl groups, respectively. A selective cyclooxygenase 2-inhibitor, it used as a nonsteroidal anti-inflammatory drug (NSAID) for the treatment of arthritis from 2001 until 2005, when it was withdrawn following concerns of an associated increased risk of heart attack and stroke.

Chemical Information

Molecular Formula
C16H14N2O3S
Molecular Mass
314.35900
Charge
0
SMILES
Cc1onc(-c2ccccc2)c1-c1ccc(cc1)S(N)(=O)=O
InChI
InChI=1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20)
InChIKey
LNPDTQAFDNKSHK-UHFFFAOYSA-N

Alternative Names

  • 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide
  • 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide
  • Bextra
  • p-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide
  • valdecoxib
  • valdecoxibum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
278567
oboInOwl#hasDbXref
Wikipedia:Valdecoxib
core#notation
CHEBI:63634

Additional References

Wikipedia:Valdecoxib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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https://w3id.org/def/predibionto#has_side_effect30775
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chebi_ontology
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278567
oboInOwl#hasDbXref
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oboInOwl#hasAlternativeId
CHEBI:41662
oboInOwl#id
CHEBI:63634
core#notation
CHEBI:63634
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50629
oboInOwl#inSubset
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