valganciclovir
CHEBI:CHEBI_63635
Definition
The L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine.
Chemical Information
- Molecular Formula
- C14H22N6O5
- Molecular Mass
- 354.36170
- Charge
- 0
- SMILES
- CC(C)[C@H](N)C(=O)OCC(CO)OCn1cnc2c1[nH]c(N)nc2=O
- InChI
- InChI=1S/C14H22N6O5/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22)/t8?,9-/m0/s1
- InChIKey
- WPVFJKSGQUFQAP-GKAPJAKFSA-N
Alternative Names
- 2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]-3-hydroxypropyl L-valinate
- valganciclovir
Drug Classification
-
purinesView Class →
CHEBI:26401
-
L-valyl esterView Class →
CHEBI:35855
-
t262094
-
t262808
-
t262831
-
t262905
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 275891
- oboInOwl#hasDbXref
- Wikipedia:Valganciclovir
- core#notation
- CHEBI:63635
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 275891
- oboInOwl#hasDbXref
- Wikipedia:Valganciclovir
- oboInOwl#id
- CHEBI:63635
- generic_name
- Valganciclovir hydrochloride powder,
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- dosage_form
- FOR SOLUTION
- brand_name
- VALGANCICLOVIR
- brand_name_base
- VALGANCICLOVIR
- product_ndc
- 63310-2410
- application_number
- ANDA215124
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50266
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_16235
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- route
- ORAL
- package_ndc
- 63310-2410-3
- package_description
- 25 kg in 1 DRUM (63310-2410-3)
- spl_id
- edb0eac3-f3c6-0b10-e053-2995a90a89b9
- listing_expiration_date
- 20241231
- marketing_start_date
- 20110215
- labeler_name
- airis PHARMA PVT LTD
- rxcui
- 863562
- package_marketing_start_date
- 11-SEP-12
- manufacturer_name
- airis PHARMA PVT LTD
- unii
- GCU97FKN3R
- spl_set_id
- 614ff447-7e5f-4ea6-ba85-ec1f6497b360
- core#notation
- CHEBI:63635
- nui
- N0000175461
- pharm_class_moa
- DNA Polymerase Inhibitors [MoA]
- pharm_class
- Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
- active_ingredient_strength
- 450 mg/1
- active_ingredient_name
- VALGANCICLOVIR
- pharm_class_epc
- Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
- upc
- 0372205019010
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_8544
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect30810
- owl#annotatedSource
- t262986
- owl#someValuesFrom
- t838335