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nebivolol

CHEBI:CHEBI_64022

Definition

A racemate consisting of equal amounts of (R,S,S,S)-nebivolol and (S,R,R,R)-nebivolol. A cardioselective beta blocker, it has vasodilatory activity but lacks intrinsic sympathomimetic and membrane-stabilising activity. It is used as the hydrochloride salt for the management of hypertension, and as an adjunct to standard therapy in elderly patients with stable chronic heart failure.

Alternative Names

  • (1RS,1'RS)-1,1'-[(2RS,2'SR)-bis(6-fluorochroman-2-yl)]-2,2'-iminodiethanol
  • (1RS,1'RS)-2,2'-iminobis{1-[(2RS,2'SR)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol}
  • dl-nebivolol
  • nebivolol
  • nebivololum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
31555
oboInOwl#hasDbXref
Wikipedia:Nebivolol
core#notation
CHEBI:64022

Additional References

Wikipedia:Nebivolol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_description
30 BLISTER PACK in 1 CARTON (0904-7226-04) / 1 TABLET in 1 BLISTER PACK
package_ndc
31722-585-32
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
Lifestar Pharma LLC
dosage_form
POWDER
marketing_start_date
20100414
application_number
NDA021742
product_ndc
51407-486
rxcui
827075
manufacturer_name
Lifestar Pharma LLC
active_ingredient_strength
25 kg/25kg
nui
N0000000161
active_ingredient_name
NEBIVOLOL HYDROCHLORIDE
unii
JGS34J7L9I
spl_set_id
126de78c-fb3d-4a53-9aaf-f2dfe1ac2a2f
upc
0382804120901
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
31555
oboInOwl#hasDbXref
Wikipedia:Nebivolol
oboInOwl#id
CHEBI:64022
generic_name
Nebivolol Hydrochloride
brand_name
Bystolic
brand_name_base
Bystolic
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35530
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_64021
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020323
core#notation
CHEBI:64022
pharm_class_moa
Adrenergic beta-Antagonists [MoA]
pharm_class
beta-Adrenergic Blocker [EPC]
pharm_class_epc
beta-Adrenergic Blocker [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
route
ORAL
spl_id
4a2bc2d9-dc34-4873-ae9e-287810a256d8
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect30969
owl#annotatedSource
t266441
owl#someValuesFrom
t3029620
package_marketing_start_date
08-DEC-07