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Dimercaprol

CHEBI:CHEBI_64198

Definition

A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Chemical Information

Molecular Formula
C3H8OS2
Molecular Mass
124.22500
Charge
0
SMILES
OCC(S)CS
InChI
InChI=1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2
InChIKey
WQABCVAJNWAXTE-UHFFFAOYSA-N

Alternative Names

  • 1,2-dimercapto-3-propanol
  • 1,2-dithioglycerol
  • 2,3-dimercapto-1-propanol
  • 2,3-Dimercapto-1-propanol
  • 2,3-dimercaptol-1-propanol
  • 2,3-dimercaptopropanol
  • 2,3-disulfanylpropan-1-ol
  • 2,3-dithiopropanol
  • 2,3-mercaptopropan-1-ol
  • 2,3-Mercaptopropanol
  • 3-hydroxy-1,2-propanedithiol
  • alpha,beta-dithioglycerol
  • BAL
  • British anti-lewisite
  • British anti-Lewisite
  • British antilewisite
  • dimercaprol
  • dimercaprolum
  • dimercaptopropanol
  • dithioglycerine
  • dithioglycerol
  • sulfactin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3445
oboInOwl#hasDbXref
Wikipedia:Dimercaprol
core#notation
CHEBI:64198

Additional References

Wikipedia:Dimercaprol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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oboInOwl#id
CHEBI:64198
core#notation
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oboInOwl#inSubset
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RO_0000087
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