Discuss This Drug

Memantine

CHEBI:CHEBI_64312

Definition

A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.

Chemical Information

Molecular Formula
C12H21N
Molecular Mass
179.30180
Charge
0
SMILES
CC12CC3CC(C)(C1)CC(N)(C3)C2
InChI
InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3
InChIKey
BUGYDGFZZOZRHP-UHFFFAOYSA-N

Alternative Names

  • 1-Amino-3,5-dimethyladamantane
  • 1,3-Dimethyl-5-adamantanamine
  • 3,5-Dimethyl-1-adamantanamine
  • 3,5-Dimethyl-1-aminoadamantane
  • 3,5-dimethyladamantan-1-amine
  • 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
  • memantina
  • memantine
  • memantinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
6719
oboInOwl#hasDbXref
Wikipedia:Memantine
core#notation
CHEBI:64312

Additional References

Wikipedia:Memantine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

marketing_start_date
20100414
labeler_name
Siegfried Evionnaz SA
product_ndc
53746-169
package_ndc
68180-248-06
route
ORAL
spl_id
11d28105-b123-f12b-e063-6394a90a81a6
dosage_form
TABLET, COATED
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
application_number
ANDA210319
package_description
3000 TABLET, COATED in 1 BOTTLE (46708-452-42)
package_marketing_start_date
23-MAR-15
listing_expiration_date
20241231
active_ingredient_strength
28 mg/1
active_ingredient_name
MEMANTINE
upc
0368382548061
spl_set_id
710f523f-0158-4639-8ce7-57598247d48c
rxcui
996633
manufacturer_name
POLYGEN PHARMACEUTICALS INC.
unii
3O2T2PJ89D
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
6719
oboInOwl#hasDbXref
Wikipedia:Memantine
oboInOwl#hasAlternativeId
CHEBI:34832
oboInOwl#id
CHEBI:64312
generic_name
Memantine Hydrochloride Oral
brand_name
Memantine HCL
brand_name_base
Memantine HCL
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48560
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_40519
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_64325
core#notation
CHEBI:64312
pharm_class
Cholinesterase Inhibitors [MoA]
brand_name_suffix
XR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_8725
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_64325
owl#annotatedSource
t266405
owl#someValuesFrom
t3001447