Discuss This Drug

posaconazole

CHEBI:CHEBI_64355

Definition

An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug.

Chemical Information

Molecular Formula
C37H42F2N8O4
Molecular Mass
700.77740
Charge
0
SMILES
CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@@H]3CO[C@](Cn4cncn4)(C3)c3ccc(F)cc3F)cc2)c1=O
InChI
InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1
InChIKey
RAGOYPUPXAKGKH-XAKZXMRKSA-N

Alternative Names

  • 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({4-[4-(4-{1-[(2S,3S)-2-hydroxypentan-3-yl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
  • Noxafil
  • posaconazole
  • posaconazole
  • Sch 56592
  • SCH56592
  • Schering 56592

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
282446
oboInOwl#hasDbXref
Wikipedia:Posaconazole
core#notation
CHEBI:64355

Additional References

Wikipedia:Posaconazole

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
INTRAVENOUS
spl_id
d572b3fd-99b0-27c0-e053-2a95a90ac211
package_ndc
62227-008-01
marketing_start_date
20221230
package_marketing_start_date
20-JUL-19
package_description
10 kg in 1 DRUM (62227-008-01)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
GRANULE
labeler_name
SYNGENE INTERNATIONAL LIMITED
application_number
ANDA216488
product_ndc
62135-429
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
282446
oboInOwl#hasDbXref
Wikipedia:Posaconazole
oboInOwl#id
CHEBI:64355
generic_name
Posaconazole Delayed-Release
brand_name
NOXAFIL
brand_name_base
NOXAFIL
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36335
core#notation
CHEBI:64355
pharm_class
Azoles [CS]
pharm_class_cs
Azoles [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
2558607
active_ingredient_strength
1 mg/mg
pharm_class_epc
Azole Antifungal [EPC]
nui
M0002083
manufacturer_name
Fresensius Kabi USA, LLC
active_ingredient_name
POSACONAZOLE
unii
6TK1G07BHZ
spl_set_id
4d14ceab-196e-4dc3-8b21-5c4629ada161
upc
0362135429607
has_treatment
http://purl.obolibrary.org/obo/DOID_8485
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect31070
owl#annotatedSource
t266425
owl#someValuesFrom
t3794220