Discuss This Drug

pregabalin

CHEBI:CHEBI_64356

Definition

A gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.

Chemical Information

Molecular Formula
C8H17NO2
Molecular Mass
159.22610
Charge
0
SMILES
CC(C)C[C@H](CN)CC(O)=O
InChI
InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1
InChIKey
AYXYPKUFHZROOJ-ZETCQYMHSA-N

Alternative Names

  • (3S)-3-(aminomethyl)-5-methylhexanoic acid
  • (S)-3-Isobutyl GABA
  • 3-Isobutyl GABA
  • Lyrica
  • pregabalin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
187832
oboInOwl#hasDbXref
Wikipedia:Pregabalin
core#notation
CHEBI:64356

Additional References

Wikipedia:Pregabalin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_ndc
70518-3345
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
187832
oboInOwl#hasDbXref
Wikipedia:Pregabalin
oboInOwl#id
CHEBI:64356
brand_name
Pregabalin Extended Release
brand_name_base
Pregabalin Extended Release
generic_name
PREGABALIN capsules, CV
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38215
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_16865
route
ORAL
package_ndc
53869-1019-3
spl_id
40fa4f98-33aa-4720-ba20-1e8b1c973c86
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
HQ Pharma (Shandong) Co., Ltd.
dosage_form
SOLUTION
application_number
ANDA214496
marketing_start_date
20130423
listing_expiration_date
20241231
package_description
90 CAPSULE in 1 BOTTLE (68788-8360-9)
package_marketing_start_date
20240920
rxcui
1994395
manufacturer_name
Eskayef Pharmaceuticals Limited
spl_set_id
f8fe5af6-5426-60c0-e053-6294a90a133f
core#notation
CHEBI:64356
dea_schedule
CV
upc
0369238131451
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
unii
55JG375S6M
active_ingredient_strength
82.5 mg/1
active_ingredient_name
PREGABALIN
has_treatment
http://purl.obolibrary.org/obo/DOID_631
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect31083
owl#annotatedSource
t266434
owl#someValuesFrom
t3214458