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Levobunolol

CHEBI:CHEBI_6438

Definition

A cyclic ketone that is 3,4-dihydronaphthalen-1-one substituted at position 5 by a 3-(tert-butylamino)-2-hydroxypropoxy group (the S-enantiomer). A non-selective beta-adrenergic antagonist used (as its hydrochloride salt) for treatment of glaucoma.

Chemical Information

Molecular Formula
C17H25NO3
Molecular Mass
291.38534
Charge
0
SMILES
CC(C)(C)NC[C@H](O)COc1cccc2C(=O)CCCc12
InChI
InChI=1S/C17H25NO3/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3/t12-/m0/s1
InChIKey
IXHBTMCLRNMKHZ-LBPRGKRZSA-N

Alternative Names

  • (-)-Bunolol
  • (S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone
  • 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one
  • Levobunolol
  • levobunololum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:6438
DRON_00010000
1813
oboInOwl#hasDbXref
Wikipedia:Levobunolol

Additional References

Wikipedia:Levobunolol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:6438
rxcui
1150836
pharm_class
beta-Adrenergic Blocker [EPC]
active_ingredient_strength
2 kg/2kg
manufacturer_name
Bausch & Lomb Incorporated
package_marketing_start_date
19940304
active_ingredient_name
LEVOBUNOLOL HYDROCHLORIDE
unii
O90S49LDHH
spl_set_id
5ab1efbe-530b-4787-b40a-c7dbf18161e1
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1813
oboInOwl#hasDbXref
Wikipedia:Levobunolol
oboInOwl#id
CHEBI:6438
product_type
BULK INGREDIENT
listing_expiration_date
20241231
marketing_category
BULK INGREDIENT
dosage_form
SOLUTION/ DROPS
route
OPHTHALMIC
marketing_start_date
19940304
labeler_name
Bausch & Lomb Incorporated
generic_name
Levobunolol Hydrochloride
brand_name
Levobunolol Hydrochloride
brand_name_base
Levobunolol Hydrochloride
product_ndc
24208-505
spl_id
1e033456-2f30-9208-e063-6394a90a094f
package_ndc
24208-505-15
package_description
1 BOTTLE, DROPPER in 1 CARTON (24208-505-15) / 15 mL in 1 BOTTLE, DROPPER
application_number
ANDA074326
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35530
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_35008
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_72567
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect31161
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_72567
owl#annotatedSource
t266413
owl#someValuesFrom
t568670