aclidinium
CHEBI:CHEBI_65346
Definition
A carboxylic ester obtained by formal condensation between the carboxy group of 2-hydroxy(di-2-thienyl)acetic acid and the hydroxy group of N-(3-phenoxypropyl)-3-quinuclidinol. Used as its bromide salt for the long-term maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD).
Chemical Information
- Molecular Formula
- C26H30NO4S2
- Molecular Mass
- 484.65100
- Charge
- +1
- SMILES
- OC(C(=O)O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)(c1cccs1)c1cccs1
- InChI
- InChI=1S/C26H30NO4S2/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2/q+1/t20?,22-,27?/m0/s1
- InChIKey
- ASMXXROZKSBQIH-VITNCHFBSA-N
Alternative Names
- (3R)-3-[2-hydroxy(di-2-thienyl)acetoxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane
Drug Classification
-
thiophenesView Class →
CHEBI:26961
-
aromatic etherView Class →
CHEBI:35618
-
quaternary ammonium ionView Class →
CHEBI:35267
-
carboxylic esterView Class →
CHEBI:33308
-
t269363
-
t269838
-
t269867
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1303098
- core#notation
- CHEBI:65346
- oboInOwl#hasDbXref
- PMID:21628603
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1303098
- oboInOwl#id
- CHEBI:65346
- core#notation
- CHEBI:65346
- oboInOwl#hasDbXref
- PMID:21628603
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_48876
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_115239
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_850
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect31339
- owl#annotatedSource
- t269606
- owl#someValuesFrom
- t3463494