Loratadine
CHEBI:CHEBI_6538
Definition
A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Chemical Information
- Molecular Formula
- C22H23ClN2O2
- Molecular Mass
- 382.890
- Charge
- 0
- SMILES
- CCOC(=O)N1CCC(CC1)=C1C2=C(CCC3=C1N=CC=C3)C=C(Cl)C=C2
- InChI
- InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
- InChIKey
- JCCNYMKQOSZNPW-UHFFFAOYSA-N
Alternative Names
- 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester
- Aerotina
- Alarin
- Alavert
- Alerpriv
- Allerclear
- Civeran
- Claratyne
- Claritin
- ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate
- Loracert
- Loradamed
- Loradex
- Lorastine
- loratadina
- loratadine
- loratadinum
- Loratyne
- Wal-itin
Drug Classification
-
ethyl esterView Class →
CHEBI:23990
-
organochlorine compoundView Class →
CHEBI:36683
-
tertiary carboxamideView Class →
CHEBI:140326
-
N-acylpiperidineView Class →
CHEBI:48591
-
benzocycloheptapyridineView Class →
CHEBI:48593
-
t268666
-
t269138
-
t269343
-
t269352
-
t269803
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Loratadine
- DRON_00010000
- 28889
- core#notation
- CHEBI:6538
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- product_ndc
- 63868-151
- brand_name_base
- Curist Allergy Relief
- brand_name
- exchange select allergy relief
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Loratadine
- DRON_00010000
- 28889
- oboInOwl#id
- CHEBI:6538
- oboInOwl#hasAlternativeId
- CHEBI:94763
- generic_name
- loratadine 5 mg chewable tablets
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_37955
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_291342
- marketing_start_date
- 20070427
- dosage_form
- TABLET, ORALLY DISINTEGRATING
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- application_number
- ANDA077153
- spl_id
- ebfab224-98d3-435a-9812-1f16b9b1e8d9
- labeler_name
- Lil' Drug Store Products, Inc.
- package_ndc
- 62011-0248-3
- has_treatment
- http://purl.obolibrary.org/obo/DOID_8892
- owl#annotatedSource
- t269893
- owl#someValuesFrom
- t2999301
- listing_expiration_date
- 20241231
- route
- ORAL
- package_description
- 1 BOTTLE in 1 CARTON (49035-612-72) / 60 TABLET in 1 BOTTLE
- core#notation
- CHEBI:6538
- brand_name_suffix
- Allergy
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rxcui
- 1369756
- unii
- Y9DL7QPE6B
- spl_set_id
- 13c40819-24af-48f1-8371-9e32dc5339a1
- manufacturer_name
- Topco Associates LLC
- package_marketing_start_date
- 16-JUN-08
- active_ingredient_strength
- 25 kg/25kg
- pharm_class
- alpha-Adrenergic Agonist [EPC]
- upc
- 0380513001184
- active_ingredient_name
- PSEUDOEPHEDRINE SULFATE