Discuss This Drug

Loratadine

CHEBI:CHEBI_6538

Definition

A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.

Chemical Information

Molecular Formula
C22H23ClN2O2
Molecular Mass
382.890
Charge
0
SMILES
CCOC(=O)N1CCC(CC1)=C1C2=C(CCC3=C1N=CC=C3)C=C(Cl)C=C2
InChI
InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
InChIKey
JCCNYMKQOSZNPW-UHFFFAOYSA-N

Alternative Names

  • 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester
  • Aerotina
  • Alarin
  • Alavert
  • Alerpriv
  • Allerclear
  • Civeran
  • Claratyne
  • Claritin
  • ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate
  • Loracert
  • Loradamed
  • Loradex
  • Lorastine
  • loratadina
  • loratadine
  • loratadinum
  • Loratyne
  • Wal-itin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Loratadine
DRON_00010000
28889
core#notation
CHEBI:6538

Additional References

Wikipedia:Loratadine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Loratadine
DRON_00010000
28889
oboInOwl#id
CHEBI:6538
oboInOwl#hasAlternativeId
CHEBI:94763
brand_name
Curist Childrens Allergy Relief
generic_name
loratadine 5 mg chewable tablets
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_291342
brand_name_base
Curist Childrens Allergy Relief
dosage_form
TABLET, ORALLY DISINTEGRATING
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
application_number
ANDA077153
product_ndc
11523-4331
listing_expiration_date
20241231
spl_id
1bfdac5c-3bc2-47ec-9b56-95b2da1f4ff2
marketing_start_date
20200925
labeler_name
Rising Pharmaceuticals, Inc
route
ORAL
package_ndc
58602-423-24
package_description
25100 TABLET, FILM COATED, EXTENDED RELEASE in 1 DRUM (63552-039-01)
manufacturer_name
TIME CAP LABORATORIES INC
package_marketing_start_date
20050124
rxcui
1369756
unii
Y9DL7QPE6B
spl_set_id
13c40819-24af-48f1-8371-9e32dc5339a1
brand_name_suffix
Allergy and Congestion D-12 hour
active_ingredient_strength
25 kg/25kg
pharm_class
alpha-Adrenergic Agonist [EPC]
upc
0380513001184
active_ingredient_name
PSEUDOEPHEDRINE SULFATE
core#notation
CHEBI:6538
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
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owl#annotatedSource
t269893
owl#someValuesFrom
t2999301