Discuss This Drug

Losartan

CHEBI:CHEBI_6541

Definition

A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Chemical Information

Molecular Formula
C22H23ClN6O
Molecular Mass
422.91100
Charge
0
SMILES
CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InChI
InChI=1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)
InChIKey
PSIFNNKUMBGKDQ-UHFFFAOYSA-N

Alternative Names

  • losartan
  • (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol
  • (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
  • 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole
  • Losartan

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
52175
oboInOwl#hasDbXref
Wikipedia:Losartan
core#notation
CHEBI:6541

Additional References

Wikipedia:Losartan

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_ndc
0093-7368
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
GRANULE
application_number
ANDA077459
package_ndc
68788-7664-6
listing_expiration_date
20241231
spl_id
1b46a65e-1fc6-d616-e063-6394a90a12b8
marketing_start_date
20220506
route
ORAL
labeler_name
ORGANON PHARMA (UK) LIMITED
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
52175
oboInOwl#hasDbXref
Wikipedia:Losartan
oboInOwl#id
CHEBI:6541
generic_name
Losartan Potassium Tabs 25 mg, 50 mg and 100mg (common blend)
brand_name
COZAAR
brand_name_base
COZAAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_51451
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_149504
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00724207
package_description
1 kg in 1 CARTON (63415-0057-0)
rxcui
979494
unii
3ST302B24A
spl_set_id
d5f17655-cfc6-6f76-e053-2a95a90a2352
manufacturer_name
PD-Rx Pharmaceuticals, Inc.
core#notation
CHEBI:6541
pharm_class_epc
Thiazide Diuretic [EPC]
pharm_class
Angiotensin 2 Receptor Blocker [EPC]
pharm_class_pe
Increased Diuresis [PE]
pharm_class_cs
Thiazides [CS]
brand_name_suffix
50 mg
upc
0364380933052
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
package_marketing_start_date
14-MAR-09
active_ingredient_strength
.0333 kg/kg
active_ingredient_name
LOSARTAN POTASSIUM
nui
M0471776
has_treatment
http://purl.obolibrary.org/obo/DOID_576
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect6691
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_149504
owl#someValuesFrom
t1050416
owl#annotatedSource
t269833