peginesatide
CHEBI:CHEBI_66889
Definition
A heterodetic cyclic peptide composed of two identical 21-amino acid cyclic peptide units covalently bonded via a linker derived from iminodiacetic acid and beta-alanine to a lysine-branched poly(ethylene glycol) chain. Used for the treatment of anemia due to chronic kidney disease in patients on dialysis.
Chemical Information
- Molecular Formula
- C231H350N62O58S6(C2H4O)n
- Charge
- 0
Alternative Names
- peginesatide
- N(sup 6.21),N(sup 6.21')-(((N(sup 2),N(sup 6)-bis((omega-methoxypoly(oxyethylene))carbonyl)-L-lysyl-beta-alanyl)imino)bis(methylenecarbonyl))bis(acetylglycylglycyl-L-leucyl-L-tyrosyl-L-alanyl-L-cysteinyl-L-histidyl-L-methionylglycyl-L-prolyl-L-isoleucyl-L-threonyl-3-(naphthalen-1-yl)-L-alanyl-L-valyl-L-cysteinyl-L-glutaminyl-L-prolyl-L-leucyl-L-arginyl-N-methylglycyl-L-lysinamide) cyclic (6-15:6'-15')-bisdisulfide
Treatment Applications
-
atypical hemolytic-uremic syndromeView Disease →
DOID:0080301
Drug Classification
-
poly(ethylene glycol) derivativeView Class →
CHEBI:139322
-
heterodetic cyclic peptideView Class →
CHEBI:24533
-
t269523
-
t269645
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1248798
- oboInOwl#hasDbXref
- Wikipedia:Peginesatide
- core#notation
- CHEBI:66889
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1248798
- oboInOwl#hasDbXref
- Wikipedia:Peginesatide
- oboInOwl#id
- CHEBI:66889
- core#notation
- CHEBI:66889
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_66894
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_66897
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_102671
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect31483
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_66897
- owl#annotatedSource
- t269715
- owl#someValuesFrom
- t673460