Discuss This Drug

ingenol mebutate

CHEBI:CHEBI_66913

Definition

A tetracyclic diterpenoid ester obtained by formal condensation of the carboxy group of (2Z)-2-methylbut-2-enoic (angelic) acid with the 3-hydroxy group of ingenol. Used for the topical treatment of actinic keratosis.

Chemical Information

Molecular Formula
C25H34O6
Molecular Mass
430.53390
Charge
0
SMILES
[H][C@@]12C=C(CO)[C@@H](O)[C@]3(O)[C@@H](OC(=O)C(\C)=C/C)C(C)=C[C@]3([C@H](C)C[C@]3([H])[C@@]1([H])C3(C)C)C2=O
InChI
InChI=1S/C25H34O6/c1-7-12(2)22(29)31-21-13(3)10-24-14(4)8-17-18(23(17,5)6)16(20(24)28)9-15(11-26)19(27)25(21,24)30/h7,9-10,14,16-19,21,26-27,30H,8,11H2,1-6H3/b12-7-/t14-,16-,17-,18+,19-,21+,24+,25+/m1/s1
InChIKey
VDJHFHXMUKFKET-UXMMOKKRSA-N

Alternative Names

  • (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[E][10]annulen-6-yl (2Z)-2-methylbut-2-enoate
  • 3-Angeloylingenol
  • 3-Ingenyl angelate
  • Ingenol 3-angelate
  • ingenol mebutate
  • ingenoli mebutas
  • mebutate d'ingenol
  • mebutato de ingenol
  • PEP-005
  • Picato

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1242806
oboInOwl#hasDbXref
Wikipedia:Ingenol_mebutate
core#notation
CHEBI:66913

Additional References

Wikipedia:Ingenol_mebutate

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1242806
oboInOwl#hasDbXref
Wikipedia:Ingenol_mebutate
oboInOwl#id
CHEBI:66913
core#notation
CHEBI:66913
listing_expiration_date
20241231
dosage_form
POWDER, FOR SUSPENSION
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
active_ingredient_strength
100 kg/100kg
labeler_name
Sichuan Xieli Pharmaceutical Co., Ltd.
marketing_start_date
20131104
generic_name
INGENOL MEBUTATE
product_ndc
61200-037
spl_id
08b49c1a-1426-a672-e063-6394a90a2b1c
active_ingredient_name
INGENOL MEBUTATE
package_ndc
61200-037-02
package_description
.006 kg in 1 DRUM (61200-037-02)
package_marketing_start_date
25-OCT-19
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35610
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_36431
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect31556
owl#annotatedSource
t269889
owl#someValuesFrom
t673272