Mephenytoin
CHEBI:CHEBI_6757
Definition
An imidazolidine-2,4-dione (hydantoin) in which the imidazolidine nucleus carries a methyl group at N-3 and has ethyl and phenyl substituents at C-5. An anticonvulsant, it is no longer available in the USA or the UK but is still studied largely because of its interesting hydroxylation polymorphism.
Chemical Information
- Molecular Formula
- C12H14N2O2
- Molecular Mass
- 218.252
- Charge
- 0
- SMILES
- CCC1(C(=O)N(C(=O)N1)C)C2=CC=CC=C2
- InChI
- InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)
- InChIKey
- GMHKMTDVRCWUDX-UHFFFAOYSA-N
Alternative Names
- 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
- DL-Mephenytoin
- mefenitoina
- mephenytoin
- mephenytoine
- mephenytoinum
- methylphenetoin
- phenylethylmethylhydantoin
Treatment Applications
-
cerebral cavernous malformation 1View Disease →
DOID:0080491
-
posterior fossa group B ependymomaView Disease →
DOID:0081255
Drug Classification
-
imidazolidine-2,4-dioneView Class →
CHEBI:24628
-
t271951
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Mephenytoin
- DRON_00010000
- 6757
- core#notation
- CHEBI:6757
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Mephenytoin
- DRON_00010000
- 6757
- oboInOwl#id
- CHEBI:6757
- core#notation
- CHEBI:6757
- oboInOwl#hasAlternativeId
- CHEBI:91914
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35623
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_104081
- owl#annotatedSource
- t273319
- owl#someValuesFrom
- t697668