Methacholine
CHEBI:CHEBI_6804
Definition
A quaternary ammonium ion in which the nitrogen is substituted with three methyl groups and a 2-acetoxypropyl group. Parasympathomimetic bronchoconstrictor drug used in clinical diagnosis.
Chemical Information
- Molecular Formula
- C8H18NO2
- Molecular Mass
- 160.23406
- Charge
- +1
- SMILES
- CC(C[N+](C)(C)C)OC(C)=O
- InChI
- InChI=1S/C8H18NO2/c1-7(11-8(2)10)6-9(3,4)5/h7H,6H2,1-5H3/q+1
- InChIKey
- NZWOPGCLSHLLPA-UHFFFAOYSA-N
Alternative Names
- 2-acetyloxy-N,N,N-trimethylpropan-1-aminium
- Acetyl-beta-methylcholine
- Acetylmethylcholine
- MCh
- Methacholine
Treatment Applications
-
meconium aspiration syndromeView Disease →
DOID:11049
-
respiratory failureView Disease →
DOID:11162
Drug Classification
-
quaternary ammonium ionView Class →
CHEBI:35267
-
acetate esterView Class →
CHEBI:47622
-
t272370
-
t272717
-
t272916
-
t273351
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Methacholine
- DRON_00010000
- 155080
- core#notation
- CHEBI:6804
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Methacholine
- DRON_00010000
- 155080
- oboInOwl#id
- CHEBI:6804
- core#notation
- CHEBI:6804
- dosage_form
- POWDER, FOR SOLUTION
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- route
- RESPIRATORY (INHALATION)
- marketing_start_date
- 20091123
- pharm_class
- Cholinergic Receptor Agonist [EPC]
- package_marketing_start_date
- 23-NOV-09
- active_ingredient_strength
- 100 mg/100mg
- labeler_name
- Methapharm Inc.
- generic_name
- Methacholine Chloride
- brand_name
- Provocholine Inhalation Solution
- brand_name_base
- Provocholine Inhalation Solution
- product_ndc
- 54236-010
- application_number
- NDA019193
- manufacturer_name
- Methapharm Inc.
- spl_id
- 0a238ccd-13a9-035e-e063-6294a90a1a3b
- active_ingredient_name
- METHACHOLINE CHLORIDE
- package_ndc
- 54236-010-01
- package_description
- 6 PACKAGE in 1 PACKAGE (64281-110-06) / 6 CARTON in 1 PACKAGE (64281-110-05) / 1 KIT in 1 CARTON * 1 VIAL, PLASTIC in 1 KIT / 3 mL in 1 VIAL, PLASTIC (64281-116-00) * 1 VIAL, PLASTIC in 1 KIT / 3 mL in 1 VIAL, PLASTIC (64281-115-00) * 1 VIAL, PLASTIC in 1 KIT / 3 mL in 1 VIAL, PLASTIC (64281-114-00) * 1 VIAL, PLASTIC in 1 KIT / 3 mL in 1 VIAL, PLASTIC (64281-113-00) * 1 VIAL, PLASTIC in 1 KIT / 3 mL in 1 VIAL, PLASTIC (64281-112-00) * 1 VIAL, PLASTIC in 1 KIT / 3 mL in 1 VIAL, PLASTIC (64281-111-00)
- unii
- 0W5ETF9M2K
- spl_set_id
- e8983096-65e6-41f2-8b6f-bbf0a7227307
- upc
- 0364281110057
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_38325
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_107457
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect31996
- owl#annotatedSource
- t273353
- owl#someValuesFrom
- t545942