Discuss This Drug

Doxapram

CHEBI:CHEBI_681848

Definition

A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.

Chemical Information

Molecular Formula
C24H30N2O2
Molecular Mass
378.50720
Charge
0
SMILES
CCN1CC(CCN2CCOCC2)C(C1=O)(c1ccccc1)c1ccccc1
InChI
InChI=1S/C24H30N2O2/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,22H,2,13-19H2,1H3
InChIKey
XFDJYSQDBULQSI-UHFFFAOYSA-N

Alternative Names

  • (+-)-doxapram
  • 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone
  • 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one
  • doxapram
  • Doxapram

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3637
oboInOwl#hasDbXref
Wikipedia:Doxapram
core#notation
CHEBI:681848

Additional References

Wikipedia:Doxapram

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3637
oboInOwl#hasDbXref
Wikipedia:Doxapram
oboInOwl#id
CHEBI:681848
core#notation
CHEBI:681848
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35337
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect32059
owl#annotatedSource
t273359
owl#someValuesFrom
t484523