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enzalutamide

CHEBI:CHEBI_68534

Definition

A benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with methylamine. Used for the treatment of of metastatic castration-resistant prostate cancer.

Chemical Information

Molecular Formula
C21H16F4N4O2S
Molecular Mass
464.43600
Charge
0
SMILES
CNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C1(C)C)c1ccc(C#N)c(c1)C(F)(F)F
InChI
InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)
InChIKey
WXCXUHSOUPDCQV-UHFFFAOYSA-N

Alternative Names

  • 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluoro-N-methylbenzamide
  • MDV 3100
  • MDV-3100
  • MDV3100
  • XTANDI

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Enzalutamide
DRON_00010000
1307298
core#notation
CHEBI:68534

Additional References

Wikipedia:Enzalutamide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
marketing_start_date
20120422
package_marketing_start_date
14-NOV-16
labeler_name
ScinoPharm Taiwan Ltd.
spl_id
0cdb029c-e80a-779e-e063-6394a90a0423
package_ndc
54893-0044-2
package_description
30 kg in 1 DRUM (54893-0044-2)
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Enzalutamide
DRON_00010000
1307298
oboInOwl#id
CHEBI:68534
generic_name
Enzalutamide SDD Hov A
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
CAPSULE
product_ndc
54893-0044
brand_name
Xtandi
brand_name_base
Xtandi
application_number
NDA203415
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35497
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:68534
rxcui
2390650
manufacturer_name
Astellas Pharma US, Inc.
active_ingredient_strength
.2 kg/kg
nui
N0000185607
pharm_class_moa
Androgen Receptor Antagonists [MoA]
pharm_class
Androgen Receptor Antagonists [MoA]
pharm_class_epc
Androgen Receptor Inhibitor [EPC]
active_ingredient_name
ENZALUTAMIDE
unii
93T0T9GKNU
spl_set_id
b129fdc9-1d8e-425c-a5a9-8a2ed36dfbdf
upc
0304690125990
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_3026
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect32285
owl#annotatedSource
t273372
owl#someValuesFrom
t3646880