enzalutamide
CHEBI:CHEBI_68534
Definition
A benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with methylamine. Used for the treatment of of metastatic castration-resistant prostate cancer.
Chemical Information
- Molecular Formula
- C21H16F4N4O2S
- Molecular Mass
- 464.43600
- Charge
- 0
- SMILES
- CNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C1(C)C)c1ccc(C#N)c(c1)C(F)(F)F
- InChI
- InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)
- InChIKey
- WXCXUHSOUPDCQV-UHFFFAOYSA-N
Alternative Names
- 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluoro-N-methylbenzamide
- MDV 3100
- MDV-3100
- MDV3100
- XTANDI
Drug Classification
-
benzamidesView Class →
CHEBI:22702
-
nitrileView Class →
CHEBI:18379
-
monofluorobenzenesView Class →
CHEBI:83575
-
(trifluoromethyl)benzenesView Class →
CHEBI:83565
-
imidazolidinoneView Class →
CHEBI:55370
-
thiocarbonyl compoundView Class →
CHEBI:50492
-
t272373
-
t273036
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Enzalutamide
- DRON_00010000
- 1307298
- core#notation
- CHEBI:68534
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Enzalutamide
- DRON_00010000
- 1307298
- oboInOwl#id
- CHEBI:68534
- core#notation
- CHEBI:68534
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35497
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_3026
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect32285
- owl#annotatedSource
- t273372
- owl#someValuesFrom
- t3646880