Discuss This Drug

teriflunomide

CHEBI:CHEBI_68540

Definition

An enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis.

Chemical Information

Molecular Formula
C12H9F3N2O2
Molecular Mass
270.20730
Charge
0
SMILES
C\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)C(F)(F)F
InChI
InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
InChIKey
UTNUDOFZCWSZMS-YFHOEESVSA-N

Alternative Names

  • (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
  • (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide
  • A 77-1726
  • A 771726
  • Aubagio
  • HMR 1726
  • HMR1726
  • teriflunomida
  • teriflunomide
  • teriflunomidum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:68540
DRON_00010000
1310520
oboInOwl#hasDbXref
Wikipedia:Teriflunomide

Additional References

Wikipedia:Teriflunomide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
ORAL
package_ndc
17337-0070-1
spl_id
246b4924-e00b-2ab9-e063-6394a90a5f34
package_description
1 BAG in 1 DRUM (17337-0070-1) / 1 BAG in 1 BAG / 10 kg in 1 BAG
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
TABLET, COATED
labeler_name
AIZANT DRUG RESEARCH SOLUTIONS PVT LTD
marketing_start_date
20230312
application_number
ANDA209555
product_ndc
42291-830
rxcui
1310535
manufacturer_name
AIZANT DRUG RESEARCH SOLUTIONS PVT LTD
package_marketing_start_date
30-APR-14
active_ingredient_strength
14 mg/1
active_ingredient_name
TERIFLUNOMIDE
unii
1C058IKG3B
spl_set_id
8219b4a2-fb9d-4387-ba33-96d28aad71dd
nui
N0000185501
upc
0369339169094
core#notation
CHEBI:68540
pharm_class_epc
Pyrimidine Synthesis Inhibitor [EPC]
pharm_class
Dihydroorotate Dehydrogenase Inhibitors [MoA]
pharm_class_moa
Dihydroorotate Dehydrogenase Inhibitors [MoA]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1310520
brand_name
TERIFLUNOMIDE
brand_name_base
TERIFLUNOMIDE
oboInOwl#hasDbXref
Wikipedia:Teriflunomide
oboInOwl#id
CHEBI:68540
generic_name
TERIFLUNOMIDE
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68542
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_2378
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_100821
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect32316
owl#annotatedSource
t273342
owl#someValuesFrom
t1124780