deferiprone
CHEBI:CHEBI_68554
Definition
A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
Chemical Information
- Molecular Formula
- C7H9NO2
- Molecular Mass
- 139.15190
- Charge
- 0
- SMILES
- Cc1c(O)c(=O)ccn1C
- InChI
- InChI=1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3
- InChIKey
- TZXKOCQBRNJULO-UHFFFAOYSA-N
Alternative Names
- 1,2-Dimethyl-3-hydroxypyrid-4-one
- 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
- 3-hydroxy-1,2-dimethylpyridin-4(1H)-one
- deferiprone
- Ferriprox
Treatment Applications
-
sideroblastic anemia 1View Disease →
DOID:0060063
-
pyridoxine-responsive sideroblastic anemiaView Disease →
DOID:0060066
-
autosomal dominant sideroblastic anemia 4View Disease →
DOID:0060335
-
delta beta-thalassemiaView Disease →
DOID:0080773
-
thalassemia minorView Disease →
DOID:0080774
Drug Classification
-
4-pyridonesView Class →
CHEBI:20485
-
t273005
-
t273356
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:68554
- DRON_00010000
- 11645
- oboInOwl#hasDbXref
- Wikipedia:Deferiprone
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:68554
- rxcui
- 1716268
- route
- ORAL
- package_marketing_start_date
- 16-APR-23
- active_ingredient_strength
- 360 kg/360kg
- manufacturer_name
- Taro Pharmaceuticals U.S.A., Inc.
- nui
- N0000175522
- pharm_class_epc
- Iron Chelator [EPC]
- pharm_class
- Iron Chelating Activity [MoA]
- pharm_class_moa
- Iron Chelating Activity [MoA]
- active_ingredient_name
- DEFERIPRONE
- package_ndc
- 0054-0711-28
- package_description
- 300 TABLET, COATED in 1 BOTTLE (0054-0711-28)
- unii
- 2BTY8KH53L
- spl_set_id
- c4f9e9be-39e7-4940-9cb0-f17772d7e524
- upc
- 0300540711191
- spl_id
- ed8809cb-0122-4631-b9bb-148b20ecd49e
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 11645
- oboInOwl#hasDbXref
- Wikipedia:Deferiprone
- oboInOwl#id
- CHEBI:68554
- generic_name
- DEFERIPRONE
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- listing_expiration_date
- 20241231
- dosage_form
- TABLET, COATED
- marketing_start_date
- 20230416
- labeler_name
- B.V. KATWIJK CHEMIE
- brand_name
- FERRIPROX
- brand_name_base
- FERRIPROX
- product_ndc
- 0054-0711
- application_number
- ANDA213239
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_38157
- has_treatment
- http://purl.obolibrary.org/obo/DOID_2350
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_106087
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect32378
- owl#annotatedSource
- t273273
- owl#someValuesFrom
- t2915457