Discuss This Drug

Ticagrelor

CHEBI:CHEBI_68558

Definition

A triazolopyrimidine that is an adenosine isostere; the cyclopentane ring is similar to ribose and the nitrogen-rich [1,2,3]triazolo[4,5-d]pyrimidine moiety resembles the nucleobase adenine. A platelet aggregation inhibitor which is used for prevention of thromboembolic events in patients with acute coronary syndrome.

Chemical Information

Molecular Formula
C23H28F2N6O4S
Molecular Mass
522.56800
Charge
0
SMILES
CCCSc1nc(N[C@@H]2C[C@H]2c2ccc(F)c(F)c2)c2nnn([C@@H]3C[C@H](OCCO)[C@@H](O)[C@H]3O)c2n1
InChI
InChI=1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1
InChIKey
OEKWJQXRCDYSHL-FNOIDJSQSA-N

Alternative Names

  • (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
  • (1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
  • AZD 6140
  • AZD-6140
  • AZD6140
  • Brilinta
  • ticagrelor

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1116632
oboInOwl#hasDbXref
Reaxys:15468079
core#notation
CHEBI:68558

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1116632
oboInOwl#hasDbXref
Reaxys:15468079
oboInOwl#id
CHEBI:68558
generic_name
TICAGRELOR
brand_name
BRILINTA
brand_name_base
BRILINTA
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
POWDER
marketing_start_date
20141011
labeler_name
n.v.Ajinomoto Ominchem
product_ndc
45941-3055
application_number
NDA022433
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50427
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
listing_expiration_date
20241231
route
ORAL
spl_id
e9c7c548-a673-454c-8e80-56dc99bd20f1
package_ndc
45941-3055-1
package_description
50 kg in 1 DRUM (45941-3055-1)
core#notation
CHEBI:68558
rxcui
1666334
pharm_class_moa
P2Y12 Receptor Antagonists [MoA]
pharm_class
Phenylalanine Hydroxylase Activators [MoA]
nui
N0000182143
active_ingredient_strength
35 kg/35kg
pharm_class_pe
Decreased Platelet Aggregation [PE]
pharm_class_epc
P2Y12 Platelet Inhibitor [EPC]
manufacturer_name
Amneal Pharmaceuticals NY LLC
active_ingredient_name
TICAGRELOR
package_marketing_start_date
11-OCT-14
unii
GLH0314RVC
spl_set_id
4f9bd52a-99a7-4606-92b4-456a917aabef
upc
0055154961806
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_5844
owl#annotatedSource
t273080
owl#someValuesFrom
t1090852