Discuss This Drug

rivaroxaban

CHEBI:CHEBI_68579

Definition

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery.

Chemical Information

Molecular Formula
C19H18ClN3O5S
Molecular Mass
435.880
Charge
0
SMILES
O1CC(N(CC1)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(C=4SC(=CC4)Cl)=O)=O
InChI
InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
InChIKey
KGFYHTZWPPHNLQ-AWEZNQCLSA-N

Alternative Names

  • 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide
  • BAY 59-7939
  • BAY59-7939
  • rivaroxaban
  • Xarelto

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:68579
DRON_00010000
1114195
oboInOwl#hasDbXref
Wikipedia:Rivaroxaban

Additional References

Wikipedia:Rivaroxaban

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:68579
listing_expiration_date
20241231
route
ORAL
spl_id
4d42fd56-57bd-43a6-93c9-6454028dfef4
package_ndc
50090-4469-0
marketing_start_date
20220117
dosage_form
GRANULE, FOR SUSPENSION
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
labeler_name
Uquifa Mexico, S.A. de C.V.
application_number
NDA022406
product_ndc
14501-0079
package_description
90 TABLET, FILM COATED in 1 BOTTLE (50090-4469-0)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1114195
oboInOwl#hasDbXref
Wikipedia:Rivaroxaban
oboInOwl#id
CHEBI:68579
generic_name
Rivaroxaban Microfine
brand_name
XARELTO
brand_name_base
XARELTO
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68581
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rxcui
2588066
active_ingredient_strength
155 mg/1
package_marketing_start_date
16-JAN-15
manufacturer_name
Cardinal Health 107, LLC
active_ingredient_name
RIVAROXABAN
pharm_class_epc
Factor Xa Inhibitor [EPC]
pharm_class
Factor Xa Inhibitors [MoA]
pharm_class_moa
Factor Xa Inhibitors [MoA]
unii
9NDF7JZ4M3
spl_set_id
65727928-9421-4df8-bff2-f72a9cc78069
nui
N0000175637
upc
0055154142205
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_9477
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect32425
owl#annotatedSource
t273373
owl#someValuesFrom
t3839064