ezogabine
CHEBI:CHEBI_68584
Definition
A substituted aniline that is benzene-1,2,4-triamine bearing ethoxycarbonyl and 4-fluorobenzyl substituents at positions N-1 and N-4 respectively. An anticonvulsant used to treat seizures associated with epilepsy in adults.
Chemical Information
- Molecular Formula
- C16H18FN3O2
- Molecular Mass
- 303.33140
- Charge
- 0
- SMILES
- CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)cc1N
- InChI
- InChI=1S/C16H18FN3O2/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11/h3-9,19H,2,10,18H2,1H3,(H,20,21)
- InChIKey
- PCOBBVZJEWWZFR-UHFFFAOYSA-N
Alternative Names
- D-23129
- ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate
- Ethyl 2-amino-4-((p-fluorobenzyl)amino)carbanilate
- N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester
- N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester
- Potiga
- retigabine
Treatment Applications
-
myoclonic-atonic epilepsyView Disease →
DOID:0060475
-
autoimmune epilepsyView Disease →
DOID:0080994
-
familial febrile seizures 8View Disease →
DOID:0111298
-
idiopathic generalized epilepsy 11View Disease →
DOID:0111312
-
idiopathic generalized epilepsy 12View Disease →
DOID:0111313
-
idiopathic generalized epilepsy 13View Disease →
DOID:0111314
-
idiopathic generalized epilepsy 14View Disease →
DOID:0111315
-
idiopathic generalized epilepsy 15View Disease →
DOID:0111316
-
idiopathic generalized epilepsy 2View Disease →
DOID:0111317
-
idiopathic generalized epilepsy 3View Disease →
DOID:0111318
-
idiopathic generalized epilepsy 4View Disease →
DOID:0111319
-
idiopathic generalized epilepsy 7View Disease →
DOID:0111321
-
idiopathic generalized epilepsy 8View Disease →
DOID:0111322
Drug Classification
-
carbamate esterView Class →
CHEBI:23003
-
organofluorine compoundView Class →
CHEBI:37143
-
substituted anilineView Class →
CHEBI:48975
-
secondary amino compoundView Class →
CHEBI:50995
-
t271969
-
t272317
-
t273315
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1112990
- oboInOwl#hasDbXref
- Wikipedia:Ezogabine
- core#notation
- CHEBI:68584
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1112990
- oboInOwl#hasDbXref
- Wikipedia:Ezogabine
- oboInOwl#id
- CHEBI:68584
- core#notation
- CHEBI:68584
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50510
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_29148
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_112862
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect32520
- owl#annotatedSource
- t273360
- owl#someValuesFrom
- t1088682