Discuss This Drug

fidaxomicin

CHEBI:CHEBI_68590

Definition

An 18-membered macrolide that is a fermentation product obtained from the Actinomycete Dactylosporangium aurantiacum. A narrow spectrum antibiotic used for treatment of Clostridium difficile-related infections.

Chemical Information

Molecular Formula
C52H74Cl2O18
Molecular Mass
1058.03900
Charge
0
SMILES
CC[C@H]1\C=C(C)\[C@@H](O)C\C=C\C=C(CO[C@@H]2O[C@H](C)[C@@H](OC(=O)c3c(O)c(Cl)c(O)c(Cl)c3CC)[C@H](O)[C@@H]2OC)\C(=O)OC(C\C=C(C)\C=C(C)\[C@@H]1O[C@@H]1OC(C)(C)[C@@H](OC(=O)C(C)C)[C@H](O)[C@@H]1O)[C@@H](C)O
InChI
InChI=1S/C52H74Cl2O18/c1-13-30-22-26(6)33(56)18-16-15-17-31(23-66-51-45(65-12)42(61)44(29(9)67-51)69-49(64)35-32(14-2)36(53)39(58)37(54)38(35)57)48(63)68-34(28(8)55)20-19-25(5)21-27(7)43(30)70-50-41(60)40(59)46(52(10,11)72-50)71-47(62)24(3)4/h15-17,19,21-22,24,28-30,33-34,40-46,50-51,55-61H,13-14,18,20,23H2,1-12H3/b16-15+,25-19+,26-22+,27-21+,31-17+/t28-,29-,30+,33+,34?,40-,41+,42+,43+,44-,45+,46+,50-,51-/m1/s1
InChIKey
ZVGNESXIJDCBKN-KFGPIHIUSA-N

Alternative Names

  • Dificid
  • Lipiarmicin
  • Lipiarmycin
  • OPT 80
  • OPT-80
  • PAR 101
  • PAR-101
  • Tiacumicin B

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1111103
oboInOwl#hasDbXref
Wikipedia:Fidaxomicin
core#notation
CHEBI:68590

Additional References

Wikipedia:Fidaxomicin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1111103
oboInOwl#hasDbXref
Wikipedia:Fidaxomicin
oboInOwl#id
CHEBI:68590
brand_name
DIFICID
brand_name_base
DIFICID
generic_name
FIDAXOMICIN
rxcui
2279847
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
GRANULE, FOR SUSPENSION
labeler_name
Biocon Limited
manufacturer_name
Merck Sharp & Dohme LLC
marketing_start_date
20200218
package_marketing_start_date
20200218
product_ndc
52015-700
spl_id
f158ad51-b770-257f-e053-2a95a90a5558
package_ndc
52015-700-22
package_description
1 POUCH in 1 CARTON (52015-700-22) / 1 BOTTLE, GLASS in 1 POUCH (52015-700-23) / 150 mL in 1 BOTTLE, GLASS (52015-700-21)
application_number
NDA213138
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37416
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:68590
pharm_class
Macrolide Antibacterial [EPC]
pharm_class_cs
Macrolides [CS]
active_ingredient_strength
6 kg/6kg
nui
N0000175431
active_ingredient_name
FIDAXOMICIN
unii
Z5N076G8YQ
spl_set_id
dd966338-c820-4270-b704-09ef75fa3ceb
pharm_class_epc
Macrolide Antibacterial [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_3584
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_110402
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect32544
owl#annotatedSource
t273338
owl#someValuesFrom
t3495426