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Linagliptin

CHEBI:CHEBI_68610

Definition

A xanthine that is 7H-xanthine bearing (4-methylquinazolin-2-yl)methyl, methyl, but-2-yn-1-yl and 3-aminopiperidin-1-yl substituents at positions 1, 3, 7 and 8 respectively (the R-enantiomer). Used for treatment of type II diabetes.

Chemical Information

Molecular Formula
C25H28N8O2
Molecular Mass
472.54220
Charge
0
SMILES
CC#CCn1c(nc2n(C)c(=O)n(Cc3nc(C)c4ccccc4n3)c(=O)c12)N1CCC[C@@H](N)C1
InChI
InChI=1S/C25H28N8O2/c1-4-5-13-32-21-22(29-24(32)31-12-8-9-17(26)14-31)30(3)25(35)33(23(21)34)15-20-27-16(2)18-10-6-7-11-19(18)28-20/h6-7,10-11,17H,8-9,12-15,26H2,1-3H3/t17-/m1/s1
InChIKey
LTXREWYXXSTFRX-QGZVFWFLSA-N

Alternative Names

  • 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione
  • (R)-8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methylquinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione
  • BI 1356
  • linagliptin
  • Tradjenta

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1100699
oboInOwl#hasDbXref
Wikipedia:Linagliptin
core#notation
CHEBI:68610

Additional References

Wikipedia:Linagliptin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

DRON_00010000
1100699
oboInOwl#hasDbXref
Wikipedia:Linagliptin
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68612
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_48517
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#id
CHEBI:68610
core#notation
CHEBI:68610
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0050778
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_107118
owl#annotatedSource
t276758
owl#someValuesFrom
t3511046