Discuss This Drug

abiraterone

CHEBI:CHEBI_68642

Definition

A 3beta-sterol that is androsta-5,16-dien-3beta-ol substituted at position 17 by a 3-pyridyl group. Administered as the O-acetate, it is used for treatment of metastatic castrate-resistant prostate cancer.

Chemical Information

Molecular Formula
C24H31NO
Molecular Mass
349.50900
Charge
0
SMILES
[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)C(=CC[C@@]21[H])c1cccnc1
InChI
InChI=1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3/t18-,19-,21-,22-,23-,24+/m0/s1
InChIKey
GZOSMCIZMLWJML-VJLLXTKPSA-N

Alternative Names

  • (3beta)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol
  • 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol
  • 17-(pyridin-3-yl)androsta-5,16-dien-3beta-ol
  • abiraterone

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:68642
oboInOwl#hasDbXref
Wikipedia:Abiraterone
DRON_00010000
1100072

Additional References

Wikipedia:Abiraterone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
ORAL
package_ndc
54893-0070-1
package_description
50 kg in 1 DRUM (54893-0070-1)
spl_id
8dd4a391-0a08-4976-8105-93ba260a2600
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
POWDER
labeler_name
Zhejiang Shenzhou Pharmaceutical Co., Ltd
application_number
ANDA215947
product_ndc
77382-0040
listing_expiration_date
20241231
marketing_start_date
20130731
package_marketing_start_date
14-JUL-17
core#notation
CHEBI:68642
pharm_class
Cytochrome P450 17A1 Inhibitors [MoA]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
2046585
active_ingredient_strength
1000 g/1000g
manufacturer_name
Novugen Pharma (USA) LLC
active_ingredient_name
ABIRATERONE
unii
EM5OCB9YJ6
spl_set_id
f308b463-27e4-422a-95a2-ecbbf95eee20
upc
0382293001101
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Abiraterone
DRON_00010000
1100072
generic_name
ABIRATERONE
oboInOwl#id
CHEBI:68642
brand_name
YONSA
brand_name_base
YONSA
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68640
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_35509
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112952
has_treatment
http://purl.obolibrary.org/obo/DOID_3026
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect32657
owl#annotatedSource
t276822
owl#someValuesFrom
t3992115