azilsartan
CHEBI:CHEBI_68850
Definition
A benzimidazolecarboxylic acid that is benzimidazole-7-carboxylic acid substituted at position 2 by a methoxy group and at position 1 by a 2'-[(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl group. Used (as the prodrug, azilsartan medoxomil) for treatment of hypertension.
Chemical Information
- Molecular Formula
- C25H20N4O5
- Molecular Mass
- 456.45010
- Charge
- 0
- SMILES
- CCOc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1
- InChI
- InChI=1S/C25H20N4O5/c1-2-33-24-26-20-9-5-8-19(23(30)31)21(20)29(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-25(32)34-28-22/h3-13H,2,14H2,1H3,(H,30,31)(H,27,28,32)
- InChIKey
- KGSXMPPBFPAXLY-UHFFFAOYSA-N
Alternative Names
- 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
- azilsartan
- TAK 536
- TAK-536
Drug Classification
-
aromatic etherView Class →
CHEBI:35618
-
benzimidazolecarboxylic acidView Class →
CHEBI:35688
-
1,2,4-oxadiazoleView Class →
CHEBI:46809
-
t275425
-
t275477
-
t276392
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1091643
- oboInOwl#hasDbXref
- Wikipedia:Azilsartan
- core#notation
- CHEBI:68850
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1091643
- oboInOwl#hasDbXref
- Wikipedia:Azilsartan
- oboInOwl#id
- CHEBI:68850
- core#notation
- CHEBI:68850
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_61016
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00724207
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect32756
- owl#annotatedSource
- t276778
- owl#someValuesFrom
- t1102230