Discuss This Drug

Metyrosine

CHEBI:CHEBI_6912

Definition

An L-tyrosine derivative that consists of L-tyrosine bearing an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma.

Chemical Information

Molecular Formula
C10H13NO3
Molecular Mass
195.21510
Charge
0
SMILES
C[C@](N)(Cc1ccc(O)cc1)C(O)=O
InChI
InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1
InChIKey
NHTGHBARYWONDQ-JTQLQIEISA-N

Alternative Names

  • (-)-alpha-Methyl-L-tyrosine
  • (S)-alpha-Methyltyrosine
  • alpha-methyl-L-p-tyrosine
  • alpha-methyl-L-tyrosine
  • alpha-methyl-p-tyrosine
  • alpha-methyl-para-tyrosine
  • alpha-Methyltyrosine
  • L-alpha-Methyltyrosine
  • Methyltyrosine
  • metirosina
  • metirosine
  • metirosinum
  • Metyrosine

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Metirosine
DRON_00010000
266604
core#notation
CHEBI:6912

Additional References

Wikipedia:Metirosine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Metirosine
DRON_00010000
266604
oboInOwl#id
CHEBI:6912
core#notation
CHEBI:6912
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_63932
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_111802
has_treatment
http://purl.obolibrary.org/obo/DOID_12583
owl#annotatedSource
t276831
owl#someValuesFrom
t696831