Discuss This Drug

dabigatran etexilate

CHEBI:CHEBI_70746

Definition

An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl N-pyridin-2-yl-beta-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism.

Chemical Information

Molecular Formula
C34H41N7O5
Molecular Mass
627.73320
Charge
0
SMILES
CCCCCCOC(=O)\N=C(\N)c1ccc(NCc2nc3cc(ccc3n2C)C(=O)N(CCC(=O)OCC)c2ccccn2)cc1
InChI
InChI=1S/C34H41N7O5/c1-4-6-7-10-21-46-34(44)39-32(35)24-12-15-26(16-13-24)37-23-30-38-27-22-25(14-17-28(27)40(30)3)33(43)41(20-18-31(42)45-5-2)29-11-8-9-19-36-29/h8-9,11-17,19,22,37H,4-7,10,18,20-21,23H2,1-3H3,(H2,35,39,44)
InChIKey
KSGXQBZTULBEEQ-UHFFFAOYSA-N

Alternative Names

  • dabigatran etexilate
  • ethyl N-[(2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alaninate

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1037042
oboInOwl#hasDbXref
Reaxys:15496119
core#notation
CHEBI:70746

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
2590637
listing_expiration_date
20251231
route
ORAL
package_marketing_start_date
20200506
marketing_start_date
20240812
manufacturer_name
Ascend Laboratories, LLC
spl_id
10cf4141-989e-4d64-b3e7-a96851fe73da
package_ndc
67877-474-60
package_description
60 CAPSULE, COATED PELLETS in 1 BOTTLE (67877-474-60)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1037042
oboInOwl#hasDbXref
Reaxys:15496119
oboInOwl#id
CHEBI:70746
generic_name
DABIGATRAN ETEXILATE
brand_name
Pradaxa
brand_name_base
Pradaxa
product_type
HUMAN PRESCRIPTION DRUG
marketing_category
ANDA
dosage_form
CAPSULE, COATED PELLETS
labeler_name
Ascend Laboratories, LLC
application_number
ANDA208070
product_ndc
67877-474
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_65232
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_70752
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_70751
core#notation
CHEBI:70746
active_ingredient_strength
110 mg/1
pharm_class
Thrombin Inhibitors [MoA]
active_ingredient_name
DABIGATRAN ETEXILATE MESYLATE
unii
SC7NUW5IIT
spl_set_id
834a3c5f-b723-4bcb-a560-dc305dd0d829
upc
0362332634606
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33199
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_70751
owl#annotatedSource
t276819
owl#someValuesFrom
t3862177