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dabigatran

CHEBI:CHEBI_70752

Definition

An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-beta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism.

Chemical Information

Molecular Formula
C25H25N7O3
Molecular Mass
471.51110
Charge
0
SMILES
Cn1c(CNc2ccc(cc2)C(N)=N)nc2cc(ccc12)C(=O)N(CCC(O)=O)c1ccccn1
InChI
InChI=1S/C25H25N7O3/c1-31-20-10-7-17(25(35)32(13-11-23(33)34)21-4-2-3-12-28-21)14-19(20)30-22(31)15-29-18-8-5-16(6-9-18)24(26)27/h2-10,12,14,29H,11,13,15H2,1H3,(H3,26,27)(H,33,34)
InChIKey
YBSJFWOBGCMAKL-UHFFFAOYSA-N

Alternative Names

  • dabigatran

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:70752
oboInOwl#hasDbXref
Wikipedia:Dabigatran

Additional References

Wikipedia:Dabigatran

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:70752
active_ingredient_strength
45 kg/45kg
pharm_class
Thrombin Inhibitors [MoA]
active_ingredient_name
DABIGATRAN
unii
SC7NUW5IIT
spl_set_id
cb4e6ba6-f216-4ed2-85d2-9f86f3b441ae
upc
0360505434961
rxcui
2590619
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
manufacturer_name
Boehringer Ingelheim Pharmaceuticals Inc.
package_marketing_start_date
20-MAR-17
package_description
25 kg in 1 DRUM (42765-054-25)
package_ndc
60505-4349-6
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Dabigatran
oboInOwl#id
CHEBI:70752
generic_name
Dabigatran Etexilate Oxalate
brand_name
Pradaxa
brand_name_base
Pradaxa
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
CAPSULE, COATED PELLETS
product_ndc
42765-054
application_number
ANDA208070
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77020
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
listing_expiration_date
20241231
route
ORAL
labeler_name
Sichuan Qingmu Pharmaceutical Co., Ltd.
marketing_start_date
20140325
spl_id
f2fd91aa-d232-6186-e053-2a95a90a11d3
has_treatment
http://purl.obolibrary.org/obo/DOID_0111900
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_70746
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33223
owl#annotatedSource
t276733
owl#someValuesFrom
t276627