perampanel
CHEBI:CHEBI_71013
Definition
A member of the class of bipyridines that is 2,3'-bipyridin-6'-one substituted at positions 1' and 5' by phenyl and 2-cyanophenyl groups respectively. Used as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy.
Chemical Information
- Molecular Formula
- C23H15N3O
- Molecular Mass
- 349.38470
- Charge
- 0
- SMILES
- O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N
- InChI
- InChI=1S/C23H15N3O/c24-15-17-8-4-5-11-20(17)21-14-18(22-12-6-7-13-25-22)16-26(23(21)27)19-9-2-1-3-10-19/h1-14,16H
- InChIKey
- PRMWGUBFXWROHD-UHFFFAOYSA-N
Alternative Names
- 2-(6'-oxo-1'-phenyl-1',6'-dihydro-2,3'-bipyridin-5'-yl)benzonitrile
- 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one
- E 2007
- E2007
- ER-155055-90
- Fycompa
- perampanel
- perampanelum
Treatment Applications
-
early onset absence epilepsyView Disease →
DOID:0050708
-
pontocerebellar hypoplasia type 3View Disease →
DOID:0060272
-
absence epilepsyView Disease →
DOID:0070309
-
pyridoxine-dependent epilepsyView Disease →
DOID:0080768
-
benign familial infantile seizures 1View Disease →
DOID:0081114
-
benign familial infantile seizures 2View Disease →
DOID:0081115
-
benign familial infantile seizures 3View Disease →
DOID:0081116
-
benign familial infantile seizures 4View Disease →
DOID:0081117
-
benign familial infantile seizures 5View Disease →
DOID:0081118
-
benign familial infantile seizures 6View Disease →
DOID:0081119
-
idiopathic generalized epilepsy 10View Disease →
DOID:0111292
-
familial febrile seizures 5View Disease →
DOID:0111306
-
familial febrile seizures 11View Disease →
DOID:0111308
-
familial febrile seizures 6View Disease →
DOID:0111309
-
idiopathic generalized epilepsy 5View Disease →
DOID:0111320
-
idiopathic generalized epilepsy 9View Disease →
DOID:0111323
-
progressive myoclonus epilepsy 1BView Disease →
DOID:0111448
-
progressive myoclonus epilepsy 1AView Disease →
DOID:0111452
-
reflex epilepsyView Disease →
DOID:2548
-
childhood absence epilepsyView Disease →
DOID:1825
-
obsolete atonic epilepsyView Disease →
DOID:2546
-
partial sensory epilepsyView Disease →
DOID:3330
Drug Classification
-
nitrileView Class →
CHEBI:18379
-
pyridoneView Class →
CHEBI:38183
-
bipyridinesView Class →
CHEBI:50511
-
t275861
-
t276052
-
t276573
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1356552
- oboInOwl#hasDbXref
- Wikipedia:Perampanel
- core#notation
- CHEBI:71013
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1356552
- oboInOwl#hasDbXref
- Wikipedia:Perampanel
- oboInOwl#id
- CHEBI:71013
- core#notation
- CHEBI:71013
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_71014
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_27991
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_3534
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_112863
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect33236
- owl#annotatedSource
- t280281
- owl#someValuesFrom
- t3009165