perampanel

CHEBI:CHEBI_71013

Definition

A member of the class of bipyridines that is 2,3'-bipyridin-6'-one substituted at positions 1' and 5' by phenyl and 2-cyanophenyl groups respectively. Used as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy.

Chemical Information

Molecular Formula
C23H15N3O
Molecular Mass
349.38470
Charge
0
SMILES
O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N
InChI
InChI=1S/C23H15N3O/c24-15-17-8-4-5-11-20(17)21-14-18(22-12-6-7-13-25-22)16-26(23(21)27)19-9-2-1-3-10-19/h1-14,16H
InChIKey
PRMWGUBFXWROHD-UHFFFAOYSA-N

Alternative Names

  • 2-(6'-oxo-1'-phenyl-1',6'-dihydro-2,3'-bipyridin-5'-yl)benzonitrile
  • 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one
  • E 2007
  • E2007
  • ER-155055-90
  • Fycompa
  • perampanel
  • perampanelum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1356552
oboInOwl#hasDbXref
Wikipedia:Perampanel
core#notation
CHEBI:71013

Additional References

Wikipedia:Perampanel

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1356552
oboInOwl#hasDbXref
Wikipedia:Perampanel
oboInOwl#id
CHEBI:71013
brand_name
Fycompa
brand_name_base
Fycompa
generic_name
Perampanel (3/4 Hydrate)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
SUSPENSION
marketing_start_date
20161003
product_ndc
11071-903
labeler_name
Eisai Manufacturing Ltd
application_number
NDA208277
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_71014
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_27991
rxcui
2641919
pharm_class_moa
AMPA Receptor Antagonists [MoA]
pharm_class
AMPA Receptor Antagonists [MoA]
active_ingredient_strength
12 mg/1
package_marketing_start_date
30-MAR-23
nui
N0000191278
active_ingredient_name
PERAMPANEL HYDRATE (4:3)
manufacturer_name
Catalyst Pharmaceuticals, Inc.
unii
H821664NPK
spl_set_id
ec812ea3-de3a-4271-957c-db8f692d1ae3
upc
0369616290381
pharm_class_epc
Noncompetitive AMPA Glutamate Receptor Antagonist [EPC]
package_description
30 TABLET in 1 BOTTLE (62856-278-30)
listing_expiration_date
20241231
route
ORAL
spl_id
f7a217c3-ad6a-410f-aef2-9545d2068694
package_ndc
11071-903-01
core#notation
CHEBI:71013
dea_schedule
CIII
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_3534
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112863
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33236
owl#annotatedSource
t280281
owl#someValuesFrom
t3009165