Discuss This Drug

omacetaxine mepesuccinate

CHEBI:CHEBI_71019

Definition

A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia.

Chemical Information

Molecular Formula
C29H39NO9
Molecular Mass
545.62130
Charge
0
SMILES
[H][C@@]12[C@H](OC(=O)[C@@](O)(CCCC(C)(C)O)CC(=O)OC)C(OC)=C[C@@]11CCCN1CCc1cc3OCOc3cc21
InChI
InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m1/s1
InChIKey
HYFHYPWGAURHIV-JFIAXGOJSA-N

Alternative Names

  • (-)-homoharringtonine
  • (2'R,3S,4S,5R)-(-)-homoharringtonine
  • CGX-635
  • Homoharringtonine
  • mepesuccinate d'omacetaxine
  • mepesuccinato de omacetaxina
  • omacetaxine mepesuccinate
  • omacetaxini mepesuccinas
  • Synribo

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
27100
oboInOwl#hasDbXref
Wikipedia:Omacetaxine_mepesuccinate
core#notation
CHEBI:71019

Additional References

Wikipedia:Omacetaxine_mepesuccinate

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
27100
oboInOwl#hasDbXref
Wikipedia:Omacetaxine_mepesuccinate
oboInOwl#id
CHEBI:71019
core#notation
CHEBI:71019
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48001
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_3540
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33243
owl#annotatedSource
t280285
owl#someValuesFrom
t3001789