Discuss This Drug

Carglumic acid

CHEBI:CHEBI_71028

Definition

A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia.

Chemical Information

Molecular Formula
C6H10N2O5
Molecular Mass
190.15400
Charge
0
SMILES
NC(=O)N[C@@H](CCC(O)=O)C(O)=O
InChI
InChI=1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1
InChIKey
LCQLHJZYVOQKHU-VKHMYHEASA-N

Alternative Names

  • (2S)-2-(carbamoylamino)pentanedioic acid
  • acide carglumique
  • acido carglumico
  • acidum carglumicum
  • Carbaglu
  • Carbamino-L-glutamic acid
  • Carbamylglutamic acid
  • carglumic acid
  • L-N-Carbamoylglutamic acid
  • N-carbamoyl-L-glutamic acid
  • Ureidoglutaric acid

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
401713
oboInOwl#hasDbXref
Wikipedia:Carglumic_acid
core#notation
CHEBI:71028

Additional References

Wikipedia:Carglumic_acid

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
401713
brand_name
Carglumic Acid
brand_name_base
Carglumic Acid
generic_name
CARGLUMIC ACID
oboInOwl#hasDbXref
Wikipedia:Carglumic_acid
oboInOwl#id
CHEBI:71028
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
TABLET, FOR SUSPENSION
marketing_start_date
20100318
labeler_name
Navinta LLC
product_ndc
46438-0658
application_number
ANDA213395
spl_id
8d401803-2e7e-cc9f-e053-2a95a90ad0af
package_ndc
46438-0658-0
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_71033
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:71028
rxcui
905394
active_ingredient_strength
35 kg/35kg
package_marketing_start_date
01-FEB-20
manufacturer_name
Navinta LLC
active_ingredient_name
CARGLUMIC ACID
package_description
25 kg in 1 DRUM (46438-0658-0)
unii
5L0HB4V1EW
spl_set_id
59e73eb8-edf8-4fad-93c2-deb6b23497f8
nui
N0000184143
pharm_class_epc
Carbamoyl Phosphate Synthetase 1 Activator [EPC]
pharm_class
Carbamoyl Phosphate Synthetase 1 Activators [MoA]
pharm_class_moa
Carbamoyl Phosphate Synthetase 1 Activators [MoA]
upc
0335573459604
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0112258
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113625
owl#annotatedSource
t280219
owl#someValuesFrom
t3103886