Discuss This Drug

bepotastine

CHEBI:CHEBI_71204

Definition

An ether that is (S)-(4-chlorophenyl)(pyridin-2-yl)methanol in which the hydroxyl hydrogen is substituted by a 1-(3-carboxypropyl)piperidin-4-yl group. A topical, selective and non-sedating histamine (H1) receptor antagonist used (as its benzenesulfonate salt) for treatment of itching associated with allergic conjunctivitis.

Chemical Information

Molecular Formula
C21H25ClN2O3
Molecular Mass
388.88800
Charge
0
SMILES
OC(=O)CCCN1CCC(CC1)O[C@@H](c1ccc(Cl)cc1)c1ccccn1
InChI
InChI=1S/C21H25ClN2O3/c22-17-8-6-16(7-9-17)21(19-4-1-2-12-23-19)27-18-10-14-24(15-11-18)13-3-5-20(25)26/h1-2,4,6-9,12,18,21H,3,5,10-11,13-15H2,(H,25,26)/t21-/m0/s1
InChIKey
YWGDOWXRIALTES-NRFANRHFSA-N

Alternative Names

  • (+)-4-(((S)-p-Chloro-alpha-2-pyridylbenzyl)oxy)-1-piperidinebutyric acid
  • 4-((4-Chlorophenyl)-2-pyridinylmethoxy)-1-piperidinebutanoic acid
  • bepotastina
  • bepotastine
  • bepotastinum
  • betotastine

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:71204
oboInOwl#hasDbXref
Wikipedia:Bepotastine
DRON_00010000
863035

Additional References

Wikipedia:Bepotastine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:71204
rxcui
863042
pharm_class
Histamine-1 Receptor Antagonist [EPC]
route
OPHTHALMIC
package_marketing_start_date
01-NOV-11
active_ingredient_strength
10 kg/10kg
manufacturer_name
Somerset Therapeutics, LLC
active_ingredient_name
BEPOTASTINE BESILATE
package_ndc
24208-630-10
package_description
1 BOTTLE, DROPPER in 1 CARTON (24208-630-10) / 10 mL in 1 BOTTLE, DROPPER
unii
6W18MO1QR3
spl_set_id
995f4fe0-d861-4137-8090-a8ffc71c46f4
upc
0370069711019
spl_id
ce72ab26-85a1-4fb5-a605-80bebe22f929
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Bepotastine
DRON_00010000
863035
oboInOwl#id
CHEBI:71204
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
marketing_start_date
20090820
dosage_form
SOLUTION/ DROPS
labeler_name
UBE Corporation
generic_name
Bepotastine Besilate Ophthalmic Solution 1.5%
brand_name
Bepotastine Besilate Ophthalmic Solution 1.5%
brand_name_base
Bepotastine Besilate Ophthalmic Solution 1.5%
product_ndc
24208-630
application_number
ANDA214588
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_71202
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_100053
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33281
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_71202
owl#annotatedSource
t280264
owl#someValuesFrom
t651036