telavancin

CHEBI:CHEBI_71229

Definition

A glycopeptide that is vancomycin substituted at position N-3'' by a 2-(decylamino)ethyl group and at position C-29 by a (phosphonomethyl)aminomethyl group. Used as its hydrochloride salt for treatment of adults with complicated skin and skin structure infections caused by bacteria.

Chemical Information

Molecular Formula
C80H106Cl2N11O27P
Molecular Mass
1755.63500
Charge
0
SMILES
CCCCCCCCCCNCCN[C@@]1(C)C[C@@H](O[C@@H](C)[C@H]1O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc1c2Oc3ccc(cc3Cl)[C@@H](O)[C@@H](NC(=O)[C@@H](CC(C)C)NC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]4C(=O)N[C@@H]([C@H](O)c5ccc(Oc1cc3c2)c(Cl)c5)C(=O)N[C@H](C(O)=O)c1cc(O)c(CNCP(O)(O)=O)c(O)c1-c1cc4ccc1O
InChI
InChI=1S/C80H106Cl2N11O27P/c1-7-8-9-10-11-12-13-14-21-85-22-23-87-80(5)32-57(115-37(4)71(80)103)119-70-68(102)67(101)55(34-94)118-79(70)120-69-53-28-41-29-54(69)117-52-20-17-40(27-46(52)82)65(99)63-77(109)91-61(78(110)111)43-30-50(96)44(33-86-35-121(112,113)114)66(100)58(43)42-25-38(15-18-49(42)95)59(74(106)93-63)90-75(107)60(41)89-73(105)48(31-56(83)97)88-76(108)62(92-72(104)47(84-6)24-36(2)3)64(98)39-16-19-51(116-53)45(81)26-39/h15-20,25-30,36-37,47-48,55,57,59-65,67-68,70-71,79,84-87,94-96,98-103H,7-14,21-24,31-35H2,1-6H3,(H2,83,97)(H,88,108)(H,89,105)(H,90,107)(H,91,109)(H,92,104)(H,93,106)(H,110,111)(H2,112,113,114)/t37-,47+,48-,55+,57-,59+,60+,61-,62+,63-,64+,65+,67+,68-,70+,71+,79-,80-/m0/s1
InChIKey
ONUMZHGUFYIKPM-MXNFEBESSA-N

Alternative Names

  • N(3'')-[2-(decylamino)ethyl]-29-{[(phosphonomethyl)amino]methyl}vancomycin
  • telavancin
  • telavancina
  • telavancine
  • telavancinum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Telavancin
DRON_00010000
473837
core#notation
CHEBI:71229

Additional References

Wikipedia:Telavancin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Telavancin
DRON_00010000
473837
oboInOwl#id
CHEBI:71229
rxcui
1728085
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20251231
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
route
INTRAVENOUS
marketing_start_date
20030218
package_marketing_start_date
18-FEB-03
labeler_name
Samsung BioLogics Co. LTD
manufacturer_name
Cumberland Pharmaceuticals Inc.
generic_name
Telavancin Hydrochloride
brand_name
VIBATIV
brand_name_base
VIBATIV
product_ndc
65129-3104
application_number
NDA022110
spl_id
c51d7182-7734-400b-b391-209352bff218
package_ndc
65129-3104-0
package_description
5.5 kg in 1 BAG (65129-3104-0)
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_28001
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36047
core#notation
CHEBI:71229
active_ingredient_strength
1 kg/kg
pharm_class
Lipoglycopeptides [EXT]
active_ingredient_name
TELAVANCIN HYDROCHLORIDE
unii
0701472ZG0
spl_set_id
5359b759-db7c-4672-9e8a-59c93869bd91
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_2176
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_110246
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33312
owl#annotatedSource
t280283
owl#someValuesFrom
t651875