telavancin
CHEBI:CHEBI_71229
Definition
A glycopeptide that is vancomycin substituted at position N-3'' by a 2-(decylamino)ethyl group and at position C-29 by a (phosphonomethyl)aminomethyl group. Used as its hydrochloride salt for treatment of adults with complicated skin and skin structure infections caused by bacteria.
Chemical Information
- Molecular Formula
- C80H106Cl2N11O27P
- Molecular Mass
- 1755.63500
- Charge
- 0
- SMILES
- CCCCCCCCCCNCCN[C@@]1(C)C[C@@H](O[C@@H](C)[C@H]1O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc1c2Oc3ccc(cc3Cl)[C@@H](O)[C@@H](NC(=O)[C@@H](CC(C)C)NC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]4C(=O)N[C@@H]([C@H](O)c5ccc(Oc1cc3c2)c(Cl)c5)C(=O)N[C@H](C(O)=O)c1cc(O)c(CNCP(O)(O)=O)c(O)c1-c1cc4ccc1O
- InChI
- InChI=1S/C80H106Cl2N11O27P/c1-7-8-9-10-11-12-13-14-21-85-22-23-87-80(5)32-57(115-37(4)71(80)103)119-70-68(102)67(101)55(34-94)118-79(70)120-69-53-28-41-29-54(69)117-52-20-17-40(27-46(52)82)65(99)63-77(109)91-61(78(110)111)43-30-50(96)44(33-86-35-121(112,113)114)66(100)58(43)42-25-38(15-18-49(42)95)59(74(106)93-63)90-75(107)60(41)89-73(105)48(31-56(83)97)88-76(108)62(92-72(104)47(84-6)24-36(2)3)64(98)39-16-19-51(116-53)45(81)26-39/h15-20,25-30,36-37,47-48,55,57,59-65,67-68,70-71,79,84-87,94-96,98-103H,7-14,21-24,31-35H2,1-6H3,(H2,83,97)(H,88,108)(H,89,105)(H,90,107)(H,91,109)(H,92,104)(H,93,106)(H,110,111)(H2,112,113,114)/t37-,47+,48-,55+,57-,59+,60+,61-,62+,63-,64+,65+,67+,68-,70+,71+,79-,80-/m0/s1
- InChIKey
- ONUMZHGUFYIKPM-MXNFEBESSA-N
Alternative Names
- N(3'')-[2-(decylamino)ethyl]-29-{[(phosphonomethyl)amino]methyl}vancomycin
- telavancin
- telavancina
- telavancine
- telavancinum
Treatment Applications
-
obsolete infectious ectromeliaView Disease →
DOID:3296
Drug Classification
-
glycopeptideView Class →
CHEBI:24396
-
t279401
-
t279823
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Telavancin
- DRON_00010000
- 473837
- core#notation
- CHEBI:71229
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Telavancin
- DRON_00010000
- 473837
- oboInOwl#id
- CHEBI:71229
- rxcui
- 1728085
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20251231
- dosage_form
- INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
- route
- INTRAVENOUS
- marketing_start_date
- 20030218
- package_marketing_start_date
- 18-FEB-03
- labeler_name
- Samsung BioLogics Co. LTD
- manufacturer_name
- Cumberland Pharmaceuticals Inc.
- generic_name
- Telavancin Hydrochloride
- brand_name
- VIBATIV
- brand_name_base
- VIBATIV
- product_ndc
- 65129-3104
- application_number
- NDA022110
- spl_id
- c51d7182-7734-400b-b391-209352bff218
- package_ndc
- 65129-3104-0
- package_description
- 5.5 kg in 1 BAG (65129-3104-0)
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_28001
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_36047
- core#notation
- CHEBI:71229
- active_ingredient_strength
- 1 kg/kg
- pharm_class
- Lipoglycopeptides [EXT]
- active_ingredient_name
- TELAVANCIN HYDROCHLORIDE
- unii
- 0701472ZG0
- spl_set_id
- 5359b759-db7c-4672-9e8a-59c93869bd91
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_2176
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_110246
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect33312
- owl#annotatedSource
- t280283
- owl#someValuesFrom
- t651875