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saxagliptin

CHEBI:CHEBI_71272

Definition

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-amino(3-hydroxyadamantan-1-yl)acetic acid with the amino group of (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Used in its monohydrate form for the treatment of Type II diabetes.

Chemical Information

Molecular Formula
C18H25N3O2
Molecular Mass
315.41000
Charge
0
SMILES
[H][C@]12C[C@@H](C#N)N(C(=O)[C@@H](N)C34CC5CC(CC(O)(C5)C3)C4)[C@@]1([H])C2
InChI
InChI=1S/C18H25N3O2/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17/h10-15,23H,1-7,9,20H2/t10?,11?,12-,13+,14+,15-,17?,18?/m1/s1
InChIKey
QGJUIPDUBHWZPV-SGTAVMJGSA-N

Alternative Names

  • (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrile
  • (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
  • BMS 477118
  • BMS-477118
  • saxagliptin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:71272
DRON_00010000
857974
oboInOwl#hasDbXref
Wikipedia:Saxagliptin

Additional References

Wikipedia:Saxagliptin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
TABLET, FILM COATED, EXTENDED RELEASE
marketing_start_date
20130629
labeler_name
Pliva Hrvatska d.o.o.
spl_id
0bfe10bc-64b4-2250-e063-6394a90a2b60
package_ndc
50370-0039-1
application_number
ANDA205980
product_ndc
82245-0119
rxcui
1043582
package_marketing_start_date
29-JUN-13
manufacturer_name
Glenmark Pharmaceuticals Inc., USA
package_description
60 kg in 1 DRUM (50370-0039-1)
core#notation
CHEBI:71272
active_ingredient_strength
1 kg/kg
active_ingredient_name
SAXAGLIPTIN HYDROCHLORIDE DIHYDRATE
unii
4N19ON48ZN
pharm_class
Dipeptidyl Peptidase 4 Inhibitors [MoA]
brand_name_suffix
XR
spl_set_id
6e8d8c4f-96eb-4b64-9c8c-4a5448a23a78
upc
0303784705933
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
857974
oboInOwl#hasDbXref
Wikipedia:Saxagliptin
oboInOwl#id
CHEBI:71272
generic_name
Saxagliptin Hydrocloride Dihydrate
brand_name
Saxagliptin and Metformin
brand_name_base
Saxagliptin and Metformin
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68612
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33345
owl#annotatedSource
t280252
owl#someValuesFrom
t3579155