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Procarbazine

CHEBI:CHEBI_71417

Definition

A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Chemical Information

Molecular Formula
C12H19N3O
Molecular Mass
221.29880
Charge
0
SMILES
CNNCc1ccc(cc1)C(=O)NC(C)C
InChI
InChI=1S/C12H19N3O/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3/h4-7,9,13-14H,8H2,1-3H3,(H,15,16)
InChIKey
CPTBDICYNRMXFX-UHFFFAOYSA-N

Alternative Names

  • 1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine
  • 2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine
  • 4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide
  • N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide
  • N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide
  • N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine
  • N-isopropyl-4-[(2-methylhydrazino)methyl]benzamide
  • N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide
  • N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide
  • p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide
  • Procarbazin
  • procarbazina
  • procarbazine
  • procarbazinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
8702
oboInOwl#hasDbXref
Wikipedia:Procarbazine
core#notation
CHEBI:71417

Additional References

Wikipedia:Procarbazine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
8702
oboInOwl#hasDbXref
Wikipedia:Procarbazine
oboInOwl#id
CHEBI:71417
core#notation
CHEBI:71417
oboInOwl#hasAlternativeId
CHEBI:8432
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35610
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_71431
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_6128
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_71431
owl#annotatedSource
t280212
owl#someValuesFrom
t845149