elvitegravir
CHEBI:CHEBI_72289
Definition
A quinolinemonocarboxylic acid that is 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid substited at position 1 by a 1-hydroxy-3-methylbutan-2-yl group and at position 6 by a 3-chloro-2-fluorobenzyl group (the S-enantiomer). It is used in combination therapy for the treatment of HIV-1 infection.
Chemical Information
- Molecular Formula
- C23H23ClFNO5
- Molecular Mass
- 447.88400
- Charge
- 0
- SMILES
- COc1cc2n(cc(C(O)=O)c(=O)c2cc1Cc1cccc(Cl)c1F)[C@H](CO)C(C)C
- InChI
- InChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1
- InChIKey
- JUZYLCPPVHEVSV-LJQANCHMSA-N
Alternative Names
- 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- elvitegravir
- elvitegravirum
- GS 9137
- GS-9137
Drug Classification
-
quinoloneView Class →
CHEBI:23765
-
quinolinemonocarboxylic acidView Class →
CHEBI:26512
-
aromatic etherView Class →
CHEBI:35618
-
organofluorine compoundView Class →
CHEBI:37143
-
monochlorobenzenesView Class →
CHEBI:83403
-
t280027
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:72289
- oboInOwl#hasDbXref
- Wikipedia:Elvitegravir
- DRON_00010000
- 1306286
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:72289
- active_ingredient_strength
- 50 kg/50kg
- active_ingredient_name
- ELVITEGRAVIR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Elvitegravir
- DRON_00010000
- 1306286
- oboInOwl#id
- CHEBI:72289
- generic_name
- Elvitegravir
- listing_expiration_date
- 20241231
- dosage_form
- POWDER
- marketing_start_date
- 20120827
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- labeler_name
- Tianish Laboratories Private Limited
- product_ndc
- 69037-0002
- spl_id
- 0faf3eb6-b5a9-cff6-e063-6294a90ad0d3
- package_ndc
- 69037-0002-1
- package_description
- 1 kg in 1 DRUM (69037-0002-1)
- package_marketing_start_date
- 27-AUG-12
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_67268
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect33395
- owl#annotatedSource
- t280282
- owl#someValuesFrom
- t3000910