apixaban
CHEBI:CHEBI_72296
Definition
A pyrazolopyridine that is 7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide substituted at position 1 by a 4-methoxyphenyl group and at position 6 by a 4-(2-oxopiperidin-1-yl)phenyl group. It is used for the prevention and treatment of thromboembolic diseases.
Chemical Information
- Molecular Formula
- C25H25N5O4
- Molecular Mass
- 459.49710
- Charge
- 0
- SMILES
- COc1ccc(cc1)-n1nc(C(N)=O)c2CCN(C(=O)c12)c1ccc(cc1)N1CCCCC1=O
- InChI
- InChI=1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)
- InChIKey
- QNZCBYKSOIHPEH-UHFFFAOYSA-N
Alternative Names
- 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
- apixaban
- apixabanum
- BMS 562247-01
- BMS-562247
- BMS-562247-01
- Eliquis
Drug Classification
-
aromatic etherView Class →
CHEBI:35618
-
lactamView Class →
CHEBI:24995
-
pyrazolopyridineView Class →
CHEBI:46699
-
piperidonesView Class →
CHEBI:48589
-
t279622
-
t279694
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1364430
- oboInOwl#hasDbXref
- Wikipedia:Apixaban
- core#notation
- CHEBI:72296
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1364430
- generic_name
- APIXABAN
- brand_name
- ELIQUIS 30-Day Starter Pack
- brand_name_base
- ELIQUIS
- oboInOwl#hasDbXref
- Wikipedia:Apixaban
- oboInOwl#id
- CHEBI:72296
- product_ndc
- 65015-897
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_68581
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- listing_expiration_date
- 20241231
- route
- ORAL
- spl_id
- 4a77fa97-9f45-4658-bbc7-0f5449b389a2
- package_ndc
- 65015-897-61
- marketing_start_date
- 20150901
- package_description
- 25 kg in 1 DRUM (65015-897-61)
- core#notation
- CHEBI:72296
- rxcui
- 1992428
- manufacturer_name
- REMEDYREPACK INC.
- active_ingredient_strength
- 6 kg/6kg
- active_ingredient_name
- APIXABAN
- pharm_class_epc
- Factor Xa Inhibitor [EPC]
- pharm_class
- Factor Xa Inhibitors [MoA]
- pharm_class_moa
- Factor Xa Inhibitors [MoA]
- nui
- N0000175637
- unii
- 3Z9Y7UWC1J
- spl_set_id
- f53ef469-4bcf-e4e2-e053-2a95a90a842a
- package_marketing_start_date
- 20121228
- upc
- 0055154061209
- brand_name_suffix
- 30-Day Starter Pack
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_2452
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect33437
- owl#annotatedSource
- t280284
- owl#someValuesFrom
- t2884042
- dosage_form
- POWDER
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- labeler_name
- Bristol-Myers Squibb Manufacturing Company Unlimited Company
- application_number
- ANDA209898