alogliptin
CHEBI:CHEBI_72323
Definition
A piperidine that is 3-methyl-2,4-dioxo-3,4-dihydropyrimidine carrying additional 2-cyanobenzyl and 3-aminopiperidin-1-yl groups at positions 1 and 2 respectively (the R-enantiomer). Used in the form of its benzoate salt for treatment of type 2 diabetes.
Chemical Information
- Molecular Formula
- C18H21N5O2
- Molecular Mass
- 339.39160
- Charge
- 0
- SMILES
- Cn1c(=O)cc(N2CCC[C@@H](N)C2)n(Cc2ccccc2C#N)c1=O
- InChI
- InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1
- InChIKey
- ZSBOMTDTBDDKMP-OAHLLOKOSA-N
Alternative Names
- 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile
- alogliptin
- alogliptina
- alogliptine
- alogliptinum
Drug Classification
-
nitrileView Class →
CHEBI:18379
-
pyrimidinesView Class →
CHEBI:39447
-
piperidinesView Class →
CHEBI:26151
-
primary amino compoundView Class →
CHEBI:50994
-
t279282
-
t280055
-
t280102
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1368001
- oboInOwl#hasDbXref
- Wikipedia:Alogliptin
- core#notation
- CHEBI:72323
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1368001
- generic_name
- Alogliptin Benzoate and Pioglitazone Hydrochloride
- oboInOwl#hasDbXref
- Wikipedia:Alogliptin
- oboInOwl#id
- CHEBI:72323
- brand_name
- Nesina
- brand_name_base
- Nesina
- product_ndc
- 70518-3976
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_68612
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_72326
- package_marketing_start_date
- 25-JAN-13
- package_description
- 30 TABLET, FILM COATED in 1 BLISTER PACK (70518-3976-0)
- package_ndc
- 47234-7102-1
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- listing_expiration_date
- 20241231
- route
- ORAL
- dosage_form
- POWDER
- marketing_start_date
- 20240106
- labeler_name
- REMEDYREPACK INC.
- spl_id
- 15593dc4-6a91-c92c-e063-6394a90a8d1b
- application_number
- NDA203414
- core#notation
- CHEBI:72323
- rxcui
- 1368036
- active_ingredient_strength
- 10 kg/10kg
- active_ingredient_name
- ALOGLIPTIN BENZOATE
- unii
- EEN99869SC
- pharm_class
- Peroxisome Proliferator-activated Receptor gamma Agonists [MoA]
- manufacturer_name
- REMEDYREPACK INC.
- spl_set_id
- 0c8dbbc9-6c85-4acd-a7bd-c55ec5829212
- upc
- 0364764250300
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect33557
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_72326
- owl#annotatedSource
- t280190
- owl#someValuesFrom
- t3005246