pomalidomide
CHEBI:CHEBI_72690
Definition
An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies.
Chemical Information
- Molecular Formula
- C13H11N3O4
- Molecular Mass
- 273.24410
- Charge
- 0
- SMILES
- Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
- InChI
- InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)
- InChIKey
- UVSMNLNDYGZFPF-UHFFFAOYSA-N
Alternative Names
- 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide
- 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione
- 4-amino-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione
- 4-Aminothalidomide
- CC 4047
- CC-4047
- pomalidomide
- Pomalyst
Treatment Applications
-
plasmacytomaView Disease →
DOID:3721
-
multiple myelomaView Disease →
DOID:9538
-
osteosclerotic myelomaView Disease →
DOID:9541
-
non-secretory myelomaView Disease →
DOID:9547
-
indolent plasma cell myelomaView Disease →
DOID:9550
-
smoldering myelomaView Disease →
DOID:9551
Drug Classification
-
isoindolesView Class →
CHEBI:24897
-
aromatic amineView Class →
CHEBI:33860
-
dicarboximideView Class →
CHEBI:35356
-
piperidonesView Class →
CHEBI:48589
-
t279576
-
t279686
-
t279791
-
t279798
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Pomalidomide
- DRON_00010000
- 1369713
- core#notation
- CHEBI:72690
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Pomalidomide
- DRON_00010000
- 1369713
- oboInOwl#id
- CHEBI:72690
- core#notation
- CHEBI:72690
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_48422
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_9513
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_9538
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113726
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect33580
- owl#annotatedSource
- t280240
- owl#someValuesFrom
- t3000323