Discuss This Drug

canagliflozin

CHEBI:CHEBI_73274

Definition

A C-glycosyl compound that is used (in its hemihydrate form) for treatment of type II diabetes via inhibition of sodium-glucose transport protein subtype 2.

Chemical Information

Molecular Formula
C24H25FO5S
Molecular Mass
444.518
Charge
0
SMILES
[C@@H]1([C@@H]([C@H]([C@@](O[C@@H]1CO)(C2=CC=C(C(=C2)CC=3SC(=CC3)C4=CC=C(C=C4)F)C)[H])O)O)O
InChI
InChI=1S/C24H25FO5S/c1-13-2-3-15(24-23(29)22(28)21(27)19(12-26)30-24)10-16(13)11-18-8-9-20(31-18)14-4-6-17(25)7-5-14/h2-10,19,21-24,26-29H,11-12H2,1H3/t19-,21-,22+,23-,24+/m1/s1
InChIKey
XTNGUQKDFGDXSJ-ZXGKGEBGSA-N

Alternative Names

  • (1S)-1,5-anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol
  • 1-(Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:73274
DRON_00010000
1373458
oboInOwl#hasDbXref
Wikipedia:Canagliflozin

Additional References

Wikipedia:Canagliflozin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
marketing_start_date
20161010
spl_id
baed9c42-06ec-52a5-e053-2995a90aff96
package_ndc
12578-615-00
package_description
25 kg in 1 CONTAINER (12578-615-00)
labeler_name
LAURUS LABS LIMITED
core#notation
CHEBI:73274
pharm_class
Sodium-Glucose Transporter 2 Inhibitors [MoA]
active_ingredient_strength
50 mg/1
upc
0350458140903
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1373458
generic_name
Canagliflozin Hemihydrate
oboInOwl#hasDbXref
Wikipedia:Canagliflozin
oboInOwl#id
CHEBI:73274
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
TABLET, FILM COATED, EXTENDED RELEASE
product_ndc
12578-615
brand_name
INVOKAMET
brand_name_base
INVOKAMET
application_number
NDA204353
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_73273
rxcui
1373473
active_ingredient_name
CANAGLIFLOZIN
unii
0SAC974Z85
package_marketing_start_date
18-OCT-16
manufacturer_name
Janssen Pharmaceuticals, Inc.
spl_set_id
4e946ba3-02c4-4a10-9d5e-f2d87b534dc3
has_treatment
http://purl.obolibrary.org/obo/DOID_0110754
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_109198
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33766
owl#annotatedSource
t283624
owl#someValuesFrom
t3056118