Discuss This Drug

Dextromoramide

CHEBI:CHEBI_74274

Definition

An N-acylpyrrolidine arising by formal condensation of pyrrolidine with (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenylbutanoic acid. An opioid analgesic that is structurally related to methadone, it is more poweful than morphine but shorter acting. It has been used (particularly as the hydrogen tartrate salt) for the treatment of severe pain, but was discontinued in the UK in 2004.

Chemical Information

Molecular Formula
C25H32N2O2
Molecular Mass
392.53380
Charge
0
SMILES
C[C@H](CN1CCOCC1)C(C(=O)N1CCCC1)(c1ccccc1)c1ccccc1
InChI
InChI=1S/C25H32N2O2/c1-21(20-26-16-18-29-19-17-26)25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27/h2-7,10-13,21H,8-9,14-20H2,1H3/t21-/m1/s1
InChIKey
INUNXTSAACVKJS-OAQYLSRUSA-N

Alternative Names

  • (+)-2,2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine
  • (+)-3-methyl-4-morpholino-2,2-diphenyl-1-(pyrrolidin-1-yl)butanone
  • (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one
  • dextromoramida
  • dextromoramide
  • dextromoramidum
  • palfium
  • palphium
  • pyrrolamidolum
  • R 875
  • SKF 5137
  • SKF-5137

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3290
oboInOwl#hasDbXref
Reaxys:96553
core#notation
CHEBI:74274

Additional References

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3290
oboInOwl#hasDbXref
Reaxys:96553
oboInOwl#id
CHEBI:74274
core#notation
CHEBI:74274
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35482
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000037
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t283662
owl#someValuesFrom
t778262