nabumetone
CHEBI:CHEBI_7443
Definition
A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
Chemical Information
- Molecular Formula
- C15H16O2
- Molecular Mass
- 228.28630
- Charge
- 0
- SMILES
- COc1ccc2cc(CCC(C)=O)ccc2c1
- InChI
- InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3
- InChIKey
- BLXXJMDCKKHMKV-UHFFFAOYSA-N
Alternative Names
- 4-(6-Methoxy-2-naphthalenyl)-2-butanone
- 4-(6-Methoxy-2-naphthyl)-2-butanone
- nabumetona
- nabumetone
- nabumetonum
- Relafen
Drug Classification
-
methyl ketoneView Class →
CHEBI:51867
-
methoxynaphthaleneView Class →
CHEBI:48851
-
t282685
-
t282773
-
t282819
-
t283702
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 31448
- oboInOwl#hasDbXref
- Wikipedia:Nabumetone
- core#notation
- CHEBI:7443
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 31448
- oboInOwl#hasDbXref
- Wikipedia:Nabumetone
- oboInOwl#id
- CHEBI:7443
- generic_name
- Nabumetone
- brand_name
- Nabumetone 500 mg
- brand_name_base
- Nabumetone 500 mg
- product_ndc
- 49706-0681
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50629
- route
- ORAL
- package_ndc
- 49706-0681-0
- spl_id
- f0e0931b-cf9a-41d0-8497-c4275f59c894
- package_description
- 25 kg in 1 DRUM (49706-0681-0)
- product_type
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- dosage_form
- POWDER
- marketing_category
- BULK INGREDIENT
- labeler_name
- Carwin Pharmaceutical Associates, LLC
- marketing_start_date
- 20180719
- application_number
- ANDA090445
- rxcui
- 2200291
- manufacturer_name
- Carwin Pharmaceutical Associates, LLC
- package_marketing_start_date
- 08-JAN-10
- unii
- LW0TIW155Z
- spl_set_id
- 583602ff-dbbe-4369-afa9-b917734ac9b1
- core#notation
- CHEBI:7443
- pharm_class
- Non-Steroidal [CS]
- nui
- N0000175722
- pharm_class_epc
- Nonsteroidal Anti-inflammatory Drug [EPC]
- pharm_class_moa
- Cyclooxygenase Inhibitors [MoA]
- pharm_class_cs
- Anti-Inflammatory Agents, Non-Steroidal [CS]
- active_ingredient_strength
- 1 kg/kg
- active_ingredient_name
- NABUMETONE
- upc
- 0371205530303
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect33822
- owl#annotatedSource
- t283720
- owl#someValuesFrom
- t933055