naftifine
CHEBI:CHEBI_7451
Definition
A tertiary amine in which the nitrogen is substituted by methyl, alpha-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections.
Chemical Information
- Molecular Formula
- C21H21N
- Molecular Mass
- 287.39810
- Charge
- 0
- SMILES
- CN(C\C=C\c1ccccc1)Cc1cccc2ccccc12
- InChI
- InChI=1S/C21H21N/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20/h2-15H,16-17H2,1H3/b11-8+
- InChIKey
- OZGNYLLQHRPOBR-DHZHZOJOSA-N
Alternative Names
- (2E)-N-methyl-N-(1-naphthylmethyl)-3-phenylprop-2-en-1-amine
- (E)-N-cinnamyl-N-methyl-1-naphthalenemethylamine
- naftifin
- naftifina
- naftifine
- naftifinum
- trans-N-cinnamyl-N-methyl-(1-naphthylmethyl)amine
Drug Classification
-
tertiary amineView Class →
CHEBI:32876
-
naphthalenesView Class →
CHEBI:25477
-
allylamine antifungal drugView Class →
CHEBI:87127
-
t282614
-
t283065
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 31476
- oboInOwl#hasDbXref
- Wikipedia:Naftifine
- core#notation
- CHEBI:7451
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 31476
- oboInOwl#hasDbXref
- Wikipedia:Naftifine
- oboInOwl#id
- CHEBI:7451
- core#notation
- CHEBI:7451
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_59285
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_8741
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect33844
- owl#annotatedSource
- t283536
- owl#someValuesFrom
- t607853