Discuss This Drug

naftifine

CHEBI:CHEBI_7451

Definition

A tertiary amine in which the nitrogen is substituted by methyl, alpha-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections.

Chemical Information

Molecular Formula
C21H21N
Molecular Mass
287.39810
Charge
0
SMILES
CN(C\C=C\c1ccccc1)Cc1cccc2ccccc12
InChI
InChI=1S/C21H21N/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20/h2-15H,16-17H2,1H3/b11-8+
InChIKey
OZGNYLLQHRPOBR-DHZHZOJOSA-N

Alternative Names

  • (2E)-N-methyl-N-(1-naphthylmethyl)-3-phenylprop-2-en-1-amine
  • (E)-N-cinnamyl-N-methyl-1-naphthalenemethylamine
  • naftifin
  • naftifina
  • naftifine
  • naftifinum
  • trans-N-cinnamyl-N-methyl-(1-naphthylmethyl)amine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:7451
DRON_00010000
31476
oboInOwl#hasDbXref
Wikipedia:Naftifine

Additional References

Wikipedia:Naftifine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:7451
rxcui
896108
package_marketing_start_date
08-JAN-10
active_ingredient_strength
1 kg/kg
pharm_class
Allylamine [CS]
active_ingredient_name
NAFTIFINE HYDROCHLORIDE
manufacturer_name
Xiromed, LLC
unii
25UR9N9041
spl_set_id
567f7418-e65c-740f-6233-741f5274fe1c
upc
0370700161173
package_description
1 TUBE in 1 CARTON (54766-770-90) / 90 g in 1 TUBE
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
31476
oboInOwl#hasDbXref
Wikipedia:Naftifine
oboInOwl#id
CHEBI:7451
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
GEL
route
TOPICAL
marketing_start_date
20180122
generic_name
Naftifine hydrochloride
brand_name
Naftifine hydrochloride
brand_name_base
Naftifine hydrochloride
product_ndc
70700-161
labeler_name
Xiromed, LLC
spl_id
7ad13433-2f93-1881-5fe6-2e0630ac70fe
package_ndc
70700-161-18
application_number
ANDA210038
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_59285
has_treatment
http://purl.obolibrary.org/obo/DOID_8741
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33844
owl#annotatedSource
t283536
owl#someValuesFrom
t607853